rac-1-Anthracen-2-yl-ethanol

Base Information

• Chemical Name: rac-1-Anthracen-2-yl-ethanol
• CAS No.: 22371-34-2
• Molecular Formula: C16H14O
• Molecular Weight: 222.287
• Hs Code.: 2906299090
• European Community (EC) Number: 683-741-8
• DSSTox Substance ID: DTXSID30399858
• Mol file: 22371-34-2.mol

Synonyms:22371-34-2;1-(Anthracen-2-yl)ethanol;rac-1-Anthracen-2-yl-ethanol;1-anthracen-2-ylethanol;1-ANTHRACEN-2-YL-ETHANOL;2-(a-hydroxyethyl)anthracene;SCHEMBL10785006;DTXSID30399858;AKOS016012275;1-(ANTHRACEN-2-YL)ETHAN-1-OL;FT-0662241

Chemical Property of rac-1-Anthracen-2-yl-ethanol

Chemical Property:

• Vapor Pressure: 1.04E-07mmHg at 25°C
• Melting Point: 162-163 °C
• Refractive Index: 1.7
• Boiling Point: 417.3 °C at 760 mmHg
• Flash Point: 186.3 °C
• PSA: 20.23000
• Density: 1.177 g/cm³
• LogP: 4.04630
• Storage Temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 222.104465066
• Heavy Atom Count: 17
• Complexity: 262

Purity/Quality:

99% ^*data from raw suppliers

rac-1-Anthracen-2-yl-ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC2=CC3=CC=CC=C3C=C2C=C1)O

Technology Process of rac-1-Anthracen-2-yl-ethanol

There total 3 articles about rac-1-Anthracen-2-yl-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

2-acetylanthracene (10210-32-9) → 1-(anthracen-2-yl)ethan-1-ol (22371-34-2)

Guidance literature:

With sodium tetrahydroborate; In methanol; dichloromethane; at 0 - 20 ℃; for 12h; Inert atmosphere;

DOI:10.1021/acs.joc.0c02848

Reference yield:

anthracene (120-12-7) → 1-(anthracen-2-yl)ethan-1-ol (22371-34-2)

Guidance literature:

Multi-step reaction with 2 steps

1: AlCl₃

2: KBH₄

With aluminium trichloride; potassium borohydride;

Reference yield:

→ 1-(anthracen-2-yl)ethan-1-ol (22371-34-2)

Guidance literature:

2-Acetylanthracen, LiAlH4 (wfr.Ae., Δ);

upstream raw materials:

2-acetylanthracene

anthracene

Downstream raw materials:

2-vinylanthracene

2-aminoanthracene

2-acetylanthracene

Refernces

• 1、 Qiu, Xu,Wang, Yachong,Su, Lingyu,Jin, Rui,Song, Song,Qin, Qixue,Li, Junhua,Zong, Baoning,Jiao, Ning. "Selective Carbon-Carbon Bond Amination with Redox-Active Aminating Reagents: A Direct Approach to Anilines?". supporting information. p. 3011 - 3016. Retrieved 2021/09/13.