Technology Process of dimethylethylbenzylamine
There total 4 articles about dimethylethylbenzylamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
N-(1-methyl-1phenylethyl)acetamide;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
Reflux;
With
sodium hydroxide;
In
tetrahydrofuran; water;
at 0 ℃;
for 2h;
pH=> 9;
Reflux;
DOI:10.1002/anie.201709894
- Guidance literature:
-
With
sodium cyanoborohydride;
Yield given. Multistep reaction;
1.) methanol, 2.) methanol, from 0 deg C to RT;
DOI:10.1021/jm960092w
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine; diphenyl phosphoryl azide / toluene / 4 h / Reflux
2.1: diethyl ether / 1 h / 0 - 20 °C / Inert atmosphere
3.1: lithium aluminium tetrahydride / tetrahydrofuran / Reflux
3.2: 2 h / 0 °C / pH > 9 / Reflux
With
lithium aluminium tetrahydride; diphenyl phosphoryl azide; triethylamine;
In
tetrahydrofuran; diethyl ether; toluene;
DOI:10.1002/anie.201709894
