Technology Process of 2,2-dimethyl-5-[2-(4-octylphenyl)ethyl]-1,3-dioxan-5-amine
There total 11 articles about 2,2-dimethyl-5-[2-(4-octylphenyl)ethyl]-1,3-dioxan-5-amine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
methanol;
at 20 ℃;
for 3h;
DOI:10.1007/s00706-011-0582-7
- Guidance literature:
-
Multi-step reaction with 3 steps
1: toluene / 6 h / Reflux; Inert atmosphere
2: potassium carbonate / tetrahydrofuran; N,N-dimethyl-formamide / 20 h / Reflux
3: palladium 10% on activated carbon; hydrogen / methanol / 3 h / 20 °C
With
palladium 10% on activated carbon; hydrogen; potassium carbonate;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide; toluene;
2: Wittig reaction;
DOI:10.1007/s00706-011-0582-7
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 3-chloro-benzenecarboperoxoic acid / chloroform / 4 h / 20 °C / Cooling with ice
2: potassium carbonate / N,N-dimethyl-formamide; tetrahydrofuran / 6 h / Reflux
3: hydrogen / palladium 10% on activated carbon / methanol / 2 h / 20 °C
With
hydrogen; potassium carbonate; 3-chloro-benzenecarboperoxoic acid;
palladium 10% on activated carbon;
In
tetrahydrofuran; methanol; chloroform; N,N-dimethyl-formamide;
2: Knoevenagel Condensation;
