N-FORMYL-DL-PHENYLALANINE

Base Information

• Chemical Name: N-FORMYL-DL-PHENYLALANINE
• CAS No.: 4289-95-6
• Molecular Formula: C10H11NO3
• Molecular Weight: 193.202
• Hs Code.: 2924299090
• Mol file: 4289-95-6.mol

Synonyms:DL-Phenylalanine, N-formyl-;N-Formyl-DL-phenylalanine;DL-Alanine,N-formyl-3-phenyl- (6CI,7CI);Alanine,N-formyl-3-phenyl- (5CI);Alanine, N-formyl-3-phenyl-, DL- (8CI);

Chemical Property of N-FORMYL-DL-PHENYLALANINE

Chemical Property:

• Melting Point: 167 °C
• Boiling Point: 449.7 °C at 760 mmHg
• Flash Point: 225.8 °C
• PSA: 66.40000
• Density: 1.235 g/cm³
• LogP: 1.45510
• Storage Temp.: ?20°C
• Solubility.: almost transparency in hot EtOH

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Formyl-DL-phenylalanine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of N-FORMYL-DL-PHENYLALANINE

There total 10 articles about N-FORMYL-DL-PHENYLALANINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

formic acid (64-18-6) + Phenylalanine (150-30-1,25191-15-5,658-69-5,67675-33-6) → N-formyl-phenylalanine (4289-95-6)

Guidance literature:

With acetic anhydride; at 20 ℃; for 1h;

DOI:10.1055/s-2004-831225

Reference yield: 100.0%

(Z)-2-formamido-3-phenylacrylic acid (74010-51-8) → N-formyl-phenylalanine (4289-95-6)

Guidance literature:

With hydrogen; for 0.00277778h;

DOI:10.1021/acs.jpca.5b06802

Reference yield: 90.0%

Phenylalanine (150-30-1,25191-15-5,658-69-5,67675-33-6) + N-(Diethylcarbamoyl)-N-methoxyformamide (146039-03-4) → N-formyl-phenylalanine (4289-95-6)

Guidance literature:

With sodium hydroxide; In 1,4-dioxane; at 60 ℃; for 58h;

DOI:10.1055/s-1992-26298

upstream raw materials:

formic acid

Phenylalanine

acetic anhydride

2-oxo-3-(phenyl)propionic acid

Downstream raw materials:

N-formyl-L-phenylalanine

(-)-(R)-N-formylphenylalanine

N-formyl-phenylalanine amide

L-phenylalanine

Refernces

• 1、 -. "ANTIFOULING AGENT FOR UNDERWATER ADHERING ORGANISMS HAVING AMINO ACID ISONITRILE SKELETON". Paragraph 0129. . Retrieved 2016/11/14.
• 2、 Fayol, Aude,Housseman, Christopher,Sun, Xiaowen,Janvier, Pierre,Bienayme, Hugues,Zhu, Jieping. "Synthesis of α-isocyano-α-alkyl(aryl)acetamides and their use in the multicomponent synthesis of 5-aminooxazole, pyrrolo[3,4-a]pyridin-5-one and 4,5,6,7-tetrahydrofuro[2,3-c]pyridine". . p. 161 - 165. Retrieved 2007/10/03.