2-Chloro-2-fluoropropane

Base Information

• Chemical Name: 2-Chloro-2-fluoropropane
• CAS No.: 420-44-0
• Molecular Formula: C3H6 Cl F
• Molecular Weight: 96.532
• DSSTox Substance ID: DTXSID00576896
• Nikkaji Number: J673.539H
• Wikidata: Q82466773
• Mol file: 420-44-0.mol

Synonyms:2-chloro-2-fluoropropane;420-44-0;2-chloro-2-fluoro-propane;HCFC-271ba;2-chloranyl-2-fluoranyl-propane;DTXSID00576896;MFCD07784193;AKOS006344782;A825730

Chemical Property of 2-Chloro-2-fluoropropane

Chemical Property:

• Vapor Pressure: 525mmHg at 25°C
• Refractive Index: 1.359
• Boiling Point: 35.3°Cat760mmHg
• Flash Point: °C
• Density: 1.016g/cm³
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 96.0142060
• Heavy Atom Count: 5
• Complexity: 33.9

Purity/Quality:

98% ^*data from raw suppliers

2-Chloro-2-fluoropropane 95% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(F)Cl

Technology Process of 2-Chloro-2-fluoropropane

There total 7 articles about 2-Chloro-2-fluoropropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-fluoropropene (1184-60-7) → 2-chloro-2-fluoropropane (420-44-0) + 1,2-dichloro-2-fluoro-propane (420-97-3) + 1-chloro-2-fluoro-propene (430-47-7) + 3-chloro-2-fluoropropene (6186-91-0)

Guidance literature:

With chlorine;

DOI:10.1021/jo00837a009

Reference yield:

1,2-propanediene (463-49-0) → 1-chloro-2,2-difluoropropane (420-99-5) + 2-chloro-2-fluoropropane (420-44-0) + 1,3-dichloro-2,2-difluoropropane (1112-36-3) + 1,2,2-trifluoro-3-chloropropane (56758-54-4)

Guidance literature:

With chlorine monofluoride; at -120 - -10 ℃; for 12h; Further byproducts given. Title compound not separated from byproducts;

DOI:10.1246/cl.1993.35

Reference yield:

2,2-dichloropropane (594-20-7) → 2,2-difluoropropane (420-45-1) + 2-chloro-2-fluoropropane (420-44-0)

Guidance literature:

With antimony(III) fluoride;

DOI:10.1021/ja01873a048 DOI:10.1021/ja01290a097

upstream raw materials:

2-chloropropene

2,2-dichloropropane

2-fluoropropene

1,2-propanediene

Downstream raw materials:

1,1,1,2,3,3,3-heptachloro-2-fluoro-propane

Refernces

• 1、 Arimura, Takashi,Kurosawa, Shigeru,Sekiya, Akira. "A New Preparative Method for 1-Chloro-2,2,3-trifluoropropane (HCFC-253ca)". . p. 35 - 36. Retrieved 2007/10/02.