Methanehydrazonamide, N-[(dimethylamino)methylene]-N,N-dimethyl-,

Base Information

• Chemical Name: Methanehydrazonamide, N-[(dimethylamino)methylene]-N,N-dimethyl-,
• CAS No.: 291307-12-5
• Molecular Formula: C₆H₁₄N₄
• Molecular Weight: 142.204
• Mol file: 291307-12-5.mol

Synonyms:Methanehydrazonamide, N-[(dimethylamino)methylene]-N,N-dimethyl-,

Chemical Property of Methanehydrazonamide, N-[(dimethylamino)methylene]-N,N-dimethyl-,

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methanehydrazonamide, N-[(dimethylamino)methylene]-N,N-dimethyl-,

There total 11 articles about Methanehydrazonamide, N-[(dimethylamino)methylene]-N,N-dimethyl-, which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) → (E)-N′-((E)-(dimethylamino)methylene)-N,N-dimethylformohydrazonamide (291307-12-5)

Guidance literature:

N,N-dimethyl-formamide; With thionyl chloride; for 24h; Cooling with ice;

With hydrazine hydrate; at 20 ℃; for 48h; Cooling with ice;

DOI:10.1021/jacs.9b06500

Reference yield: 95.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) → N,N'-bis(dimethylaminomethylene)hydrazine (16114-05-9,291307-12-5)

Guidance literature:

N,N-dimethyl-formamide; With thionyl chloride; for 24h; Cooling with ice;

With hydrazine hydrate; In N,N-dimethyl-formamide; Cooling with ice;

With sodium carbonate; In water;

Reference yield: 89.0%

diformylhydrazine (628-36-4) + tert-Butoxybis(dimethylamino)methane (5815-08-7) → N,N'-bis(dimethylaminomethylene)hydrazine (16114-05-9,291307-12-5)

Guidance literature:

Heating;

DOI:10.1055/s-0028-1083192

upstream raw materials:

diformylhydrazine

N,N-dimethyl-formamide

Diacetylhydrazin

acetone hydrazone

Downstream raw materials:

4,4'-bi-1,2,4-triazole

4-(benzimidazol-1-yl)-4H-[1,2,4]triazole

4-(4’-carboxyphenyl)-1,2,4-triazole

2-(4H-1,2,4-triazol-4-yl)acetic acid

Refernces

• 1、 Cabezas-Giménez, Juanjo,Lillo, Vanesa,Luis Nú?ez-Rico, José,Nieves Corella-Ochoa,Jover, Jesús,Galán-Mascarós, José Ramón,Vidal-Ferran, Anton. "Differentiation of Epoxide Enantiomers in the Confined Spaces of an Homochiral Cu(II) Metal-Organic Framework by Kinetic Resolution". supporting information. p. 16956 - 16965. Retrieved 2021/07/16.
• 2、 Corella-Ochoa, M. Nieves,Tapia, Jesús B.,Rubin, Heather N.,Lillo, Vanesa,González-Cobos, Jesús,Nú?ez-Rico, José Luis,Balestra, Salvador R.G.,Almora-Barrios, Neyvis,Lledós, Marina,Gu?ll-Bara, Arnau,Cabezas-Giménez, Juanjo,Escudero-Adán, Eduardo C.,Vidal-Ferran, Anton,Calero, Sofiá,Reynolds, Melissa,Martí-Gastaldo, Carlos,Galán-Mascarós, José Ramón. "Homochiral Metal-Organic Frameworks for Enantioselective Separations in Liquid Chromatography". . p. 14306 - 14316. Retrieved 2019/10/11.