Technology Process of 2-butoxy-3-ethoxy-5-formylphenylboronic acid
There total 4 articles about 2-butoxy-3-ethoxy-5-formylphenylboronic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-butoxy-1-ethoxy-5-(diethoxymethyl)-3-iodobenzene;
With
isopropylmagnesium chloride;
In
tetrahydrofuran;
at -10 ℃;
for 0.5h;
With
Trimethyl borate;
In
tetrahydrofuran;
at -10 ℃;
for 2h;
With
hydrogenchloride; sodium chloride;
In
tetrahydrofuran; water;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / N,N-dimethyl acetamide / 4 h / 60 °C
2.1: ammonium chloride / ethanol / 4 h / Reflux
3.1: isopropylmagnesium chloride / tetrahydrofuran / 0.5 h / -10 °C
3.2: 2 h / -10 °C
With
isopropylmagnesium chloride; potassium carbonate; ammonium chloride;
In
tetrahydrofuran; ethanol; N,N-dimethyl acetamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: ammonium chloride / ethanol / 4 h / Reflux
2.1: isopropylmagnesium chloride / tetrahydrofuran / 0.5 h / -10 °C
2.2: 2 h / -10 °C
With
isopropylmagnesium chloride; ammonium chloride;
In
tetrahydrofuran; ethanol;
