dichlorobis(di-tert-butylphenylphosphine)palladium(II)

Base Information

• Chemical Name: dichlorobis(di-tert-butylphenylphosphine)palladium(II)
• CAS No.: 34409-44-4
• Molecular Formula: C28H46 Cl2 P2 Pd
• Molecular Weight: 621.947
• Mol file: 34409-44-4.mol

Synonyms:Palladium,dichlorobis(di-tert-butylphenylphosphine)-, trans- (8CI); Phosphine, bis(1,1-dimethylethyl)phenyl-,palladium complex; trans-Dichlorobis(di-tert-butylphenylphosphine)palladium

Chemical Property of dichlorobis(di-tert-butylphenylphosphine)palladium(II)

Chemical Property:

• Melting Point: 260-264°C (decomposition)
• PSA: 27.18000
• LogP: 10.16060
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive.: Air & moisture sensitive
• Water Solubility.: Soluble in water and polar organic solvents.

Purity/Quality:

98%, ^*data from raw suppliers

Dichlorobis(di-tert-butylphenylphosphine)palladium(II) ^*data from reagent suppliers

Safty Information:

• Safety Statements: 36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: dichlorobis(di-tert-butylphenylphosphine)palladium(II) is used as an effective catalyst for cross-coupling reactions. Dichlorobis(di-tert-butylphenylphosphine)palladium(II) is used as catalyst in Suzuki-Miyaura coupling reactions

Technology Process of dichlorobis(di-tert-butylphenylphosphine)palladium(II)

There total 3 articles about dichlorobis(di-tert-butylphenylphosphine)palladium(II) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.8%

di(tert-butyl)chlorophosphine (13716-10-4) + palladium (7440-05-3) + phenylmagnesium bromide (100-58-3) → bis(di-tert-butylphenylphosphine)palladium(II) dichloride (34409-44-4)

Guidance literature:

palladium; With hydrogenchloride; nitric acid; cyclo-octa-1,5-diene; In ethanol; water; at 50 ℃;

di(tert-butyl)chlorophosphine; phenylmagnesium bromide; In tetrahydrofuran; ethanol; water; at 50 - 70 ℃; Temperature;

Reference yield:

Pd2Cl4(As(C(CH3)3)3)2 (78610-10-3) + di(tertbutyl)phenylphosphine (32673-25-9) → bis(di-tert-butylphenylphosphine)palladium(II) dichloride (34409-44-4)

Guidance literature:

In dichloromethane; Pt complex and org. compd. stirred together in CH2Cl2 for 3 h; removal of solvent, rerystn. (CH2Cl2-MeOH); elem. anal.;

DOI:10.1021/ic50225a006

Reference yield:

sodium tetrachloropalladate(II) + di(tertbutyl)phenylphosphine (32673-25-9) → bis(di-tert-butylphenylphosphine)palladium(II) dichloride (34409-44-4)

Guidance literature:

In methanol; (N2); dropwise addn. of a soln. of phosphine to a soln. of Pd-complex; stirring for 1 h; filtration; washing with methanol; 3 times recrystn. from MeOH/CH2Cl2 (1:1); elem. anal.;

DOI:10.1021/j100379a020

upstream raw materials:

di(tertbutyl)phenylphosphine

Pd₂Cl₄(As(C(CH₃)3)3)2

di(tert-butyl)chlorophosphine

palladium

Downstream raw materials:

[PdCH₂C(CH₃)2P(C(CH₃)3)C₆H₅]2(Cl)2

C₅H₅Pd(P(C(CH₃)3)2C₆H₅)Cl

Refernces

• 1、 -. "Preparation method of bis(ditert-butyl phenyl phosphine)palladium dichloride". Paragraph 0015-0018. . Retrieved 2020/02/17.