TRIMETHYL 1,2,3-BENZENETRICARBOXYLATE

Base Information

• Chemical Name: TRIMETHYL 1,2,3-BENZENETRICARBOXYLATE
• CAS No.: 2672-57-3
• Molecular Formula: C12H12 O6
• Molecular Weight: 252.224
• Mol file: 2672-57-3.mol

Synonyms:1,2,3-Benzenetricarboxylicacid, trimethyl ester (7CI,8CI,9CI); Hemimellitic acid, trimethyl ester (6CI);Trimethyl 1,2,3-benzenetricarboxylate; Trimethyl hemimellitate

Chemical Property of TRIMETHYL 1,2,3-BENZENETRICARBOXYLATE

Chemical Property:

• Vapor Pressure: 0.00198mmHg at 25°C
• Melting Point: 100-101 °C
• Refractive Index: 1.518
• Boiling Point: 291.2°C at 760 mmHg
• Flash Point: 123.2°C
• PSA: 78.90000
• Density: 1.241g/cm³
• LogP: 1.04640

Purity/Quality:

99% ^*data from raw suppliers

TRIMETHYL 1,2,3-BENZENETRICARBOXYLATE 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TRIMETHYL 1,2,3-BENZENETRICARBOXYLATE

There total 19 articles about TRIMETHYL 1,2,3-BENZENETRICARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.8%

trimethyl 3,6-cyclohexadiene-1,2,3-tricarboxylate (188345-42-8) → benzene-1,2,3-tricarboxylic acid trimethyl ester (2672-57-3)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In benzene; for 24h; Heating;

DOI:10.1248/cpb.45.243

Reference yield: 92.0%

methyl 2-oxo-2H-pyrane-3-carboxylate (25991-27-9) + dimethyl acetylenedicarboxylate (762-42-5) → benzene-1,2,3-tricarboxylic acid trimethyl ester (2672-57-3)

Guidance literature:

at 200 ℃; for 2h;

Reference yield: 88.0%

methyl 2-pyrone-6-carboxylate (68160-93-0) + dimethyl acetylenedicarboxylate (762-42-5) → benzene-1,2,3-tricarboxylic acid trimethyl ester (2672-57-3)

Guidance literature:

at 200 ℃; for 2h;

upstream raw materials:

methanol

benzene-1,2,3-tricarboxlic acid

γ-carbonyl-3-acenaphthene butyric acid

methyl iodide

Downstream raw materials:

C₁₆H₁₇NO₇

C₁₈H₂₁NO₇

C₁₇H₁₉NO₇

1,2,3-tris-hydroxymethyl-benzene

Refernces

• 1、 Koike, Takeshi,Tanabe, Mituharu,Takeuchi, Naoki,Tobinaga, Seisho. "Aminodienylesters. I: The cycloaddition reactions of tert- aminodienylester with α,β-unsaturated carbonyl compounds, styrenes, and quinones". . p. 243 - 248. Retrieved 2007/10/03.
• 2、 Ziegler, Thomas,Layh, Marcus,Effenberger, Franz. "Syntheses of Highly Substituted Benzenes via Diels-Alder Reactions with 2H-Pyran-2-ones". . p. 1347 - 1356. Retrieved 2007/10/02.