Bis(4-methoxyphenyl)essigsaeurechlorid

Base Information

• Chemical Name: Bis(4-methoxyphenyl)essigsaeurechlorid
• CAS No.: 7123-90-2
• Molecular Formula: C₁₆H₁₅ClO₃
• Molecular Weight: 290.746
• Mol file: 7123-90-2.mol

Synonyms:Bis(4-methoxyphenyl)essigsaeurechlorid

Chemical Property of Bis(4-methoxyphenyl)essigsaeurechlorid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Bis(4-methoxyphenyl)essigsaeurechlorid

There total 6 articles about Bis(4-methoxyphenyl)essigsaeurechlorid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2-bis-(4-methoxyphenyl)acetic acid (4541-73-5) → Bis(4-methoxyphenyl)essigsaeurechlorid (7123-90-2)

Guidance literature:

With phosphorus pentachloride; trichlorophosphate;

Reference yield:

methoxybenzene (100-66-3) → Bis(4-methoxyphenyl)essigsaeurechlorid (7123-90-2)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid / acetic acid / 40 °C / Cooling with ice

2: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 2 h / 20 °C

With oxalyl dichloride; sulfuric acid; In dichloromethane; acetic acid; N,N-dimethyl-formamide;

DOI:10.1039/c6cc05456k

Reference yield:

4-methoxymandelonitrile (33646-40-1) → Bis(4-methoxyphenyl)essigsaeurechlorid (7123-90-2)

Guidance literature:

Multi-step reaction with 3 steps

1: sulfuric acid

2: concentrated alcoholic KOH-solution

3: phosphorus oxychloride; phosphorus pentachloride

With potassium hydroxide; phosphorus pentachloride; sulfuric acid; trichlorophosphate;

upstream raw materials:

2,2-bis-(4-methoxyphenyl)acetic acid

4-methoxymandelonitrile

2,2-bis(4-methoxyphenyl)acetonitrile

4-methoxy-benzaldehyde

Downstream raw materials:

C₃₉H₅₁NO₉

C₃₅H₄₃NO₉

Bis(4-methoxyphenyl)essigsaeureanilid

Refernces

• 1、 Zhou, Xiaorong,Peng, Zhixing,Zhao, Hongyang,Zhang, Zhiyin,Lu, Ping,Wang, Yanguang. "Rh-Catalyzed annulations of: N -methoxybenzamides with ketenimines: Synthesis of 3-aminoisoindolinones and 3-diarylmethyleneisoindolinones with strong aggregation induced emission properties". supporting information. p. 10676 - 10679. Retrieved 2016/09/02.