Technology Process of 2-(2-Methoxyphenylthiomethyl)benzoic acid
There total 1 articles about 2-(2-Methoxyphenylthiomethyl)benzoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium hydroxide; hydroxylamine hydrochloride; dicyclohexyl-carbodiimide;
In
methanol;
at 20 ℃;
for 1h;
DOI:10.1021/jo00373a022
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 81 percent / P2O5, 85percent aq H3PO4 / toluene / 2 h / 100 °C / Heating
2: 92 percent / NaBH4 / ethanol / 4 h / Heating
3: 94 percent / HCl,CaCl2 / CCl4 / 1.5 h / Ambient temperature
4: 72 percent / NaH / benzene / 1. 3 h reflux; 2. room temp., overnight
5: 79 percent / KOH / ethanol; H2O / 6 h / Heating
6: 95 percent / Piperidine / pyridine / 2.5 h / Heating
7: 88 percent / SOCl2 / benzene / 1. 60-70 deg C, 2.5 h; 2. 0.5 h reflux
8: 99 percent / NH3 / benzene / Ambient temperature
With
piperidine; hydrogenchloride; potassium hydroxide; sodium tetrahydroborate; thionyl chloride; phosphoric acid; ammonia; phosphorus pentoxide; sodium hydride; calcium chloride;
In
pyridine; tetrachloromethane; ethanol; water; toluene; benzene;
DOI:10.1135/cccc19820984
