Technology Process of trans-1-ethoxy-4-(4-styrylphenoxy)benzene
There total 4 articles about trans-1-ethoxy-4-(4-styrylphenoxy)benzene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-Ethoxyphenol;
With
1-methyl-pyrrolidin-2-one; sodium hydride;
In
mineral oil;
at 20 ℃;
for 1h;
Cooling with ice;
(E)-4-fluorostilbene;
With
1-methyl-pyrrolidin-2-one;
at 20 - 145 ℃;
for 21h;
DOI:10.1016/j.tet.2013.06.074
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 18-crown-6 ether; potassium carbonate / dichloromethane; water / 72 h / 20 °C
2.1: sodium hydride; 1-methyl-pyrrolidin-2-one / mineral oil / 1 h / 20 °C / Cooling with ice
2.2: 21 h / 20 - 145 °C
With
1-methyl-pyrrolidin-2-one; 18-crown-6 ether; sodium hydride; potassium carbonate;
In
dichloromethane; water; mineral oil;
1.1: |Wittig Olefination;
DOI:10.1016/j.tet.2013.06.074
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: benzene / 48 h / Reflux
2.1: 18-crown-6 ether; potassium carbonate / dichloromethane; water / 72 h / 20 °C
3.1: sodium hydride; 1-methyl-pyrrolidin-2-one / mineral oil / 1 h / 20 °C / Cooling with ice
3.2: 21 h / 20 - 145 °C
With
1-methyl-pyrrolidin-2-one; 18-crown-6 ether; sodium hydride; potassium carbonate;
In
dichloromethane; water; mineral oil; benzene;
2.1: |Wittig Olefination;
DOI:10.1016/j.tet.2013.06.074