Technology Process of 4-(2-Chloro-phenyl)-2-(2,3-dihydro-benzofuran-5-ylethynyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulene
There total 4 articles about 4-(2-Chloro-phenyl)-2-(2,3-dihydro-benzofuran-5-ylethynyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
copper(l) iodide; palladium diacetate; triethylamine; triphenylphosphine;
In
N,N-dimethyl-formamide;
for 5h;
DOI:10.1021/jm00108a031
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 76 percent / ICl / acetic acid / 0.25 h / Ambient temperature
2: Ph3P, CuI, Et3N, palladium acetate / acetonitrile / 2 h / Ambient temperature
3: K2CO3 / methanol / 2 h / Ambient temperature
4: 39 percent / Ph3P, CuI, Et3N, palladium acetate / dimethylformamide / 5 h
With
copper(l) iodide; palladium diacetate; Iodine monochloride; potassium carbonate; triethylamine; triphenylphosphine;
In
methanol; acetic acid; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm00108a031
- Guidance literature:
-
Multi-step reaction with 3 steps
1: Ph3P, CuI, Et3N, palladium acetate / acetonitrile / 2 h / Ambient temperature
2: K2CO3 / methanol / 2 h / Ambient temperature
3: 39 percent / Ph3P, CuI, Et3N, palladium acetate / dimethylformamide / 5 h
With
copper(l) iodide; palladium diacetate; potassium carbonate; triethylamine; triphenylphosphine;
In
methanol; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm00108a031