6-Bromo-1,2-dihydronaphthalene

Base Information

• Chemical Name: 6-Bromo-1,2-dihydronaphthalene
• CAS No.: 75693-17-3
• Molecular Formula: C10H9 Br
• Molecular Weight: 209.08246
• Hs Code.: 2903999090
• DSSTox Substance ID: DTXSID70507137
• Mol file: 75693-17-3.mol

Synonyms:6-bromo-1,2-dihydronaphthalene;75693-17-3;SCHEMBL2113127;AMY7418;DTXSID70507137;LOKQHPNLNHXWSQ-UHFFFAOYSA-N;AKOS022178302

Chemical Property of 6-Bromo-1,2-dihydronaphthalene

Chemical Property:

• Vapor Pressure: 0.025mmHg at 25°C
• Refractive Index: 1.607
• Boiling Point: 256.407°C at 760 mmHg
• Flash Point: 110.747°C
• PSA: 0.00000
• Density: 1.435g/cm³
• LogP: 3.40850
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 207.98876
• Heavy Atom Count: 11
• Complexity: 162

Purity/Quality:

99%min ^*data from raw suppliers

6-Bromo-1,2-dihydronaphthalene 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2=C(C=C1)C=C(C=C2)Br

Technology Process of 6-Bromo-1,2-dihydronaphthalene

There total 4 articles about 6-Bromo-1,2-dihydronaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

7-bromo-1,2,3,4-tetrahydronaphthalen-1-ol (75693-15-1) → bromo-7 dihydro-3,4 naphthalene (75693-17-3)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; for 1.5h; Heating;

DOI:10.1021/jm00186a015

Reference yield:

7-bromo-3,4-dihydro-2H-naphthalen-1-one (32281-97-3) → bromo-7 dihydro-3,4 naphthalene (75693-17-3)

Guidance literature:

Multistep reaction; (i) Al(OiPr)3, (ii) KHSO₄;

DOI:10.1039/jr9610004794

Reference yield:

4-(4-bromophenyl)butanoic acid (35656-89-4) → bromo-7 dihydro-3,4 naphthalene (75693-17-3)

Guidance literature:

Multi-step reaction with 2 steps

1: AlCl₃ / CS₂

2: Zn, HCl

With hydrogenchloride; aluminium trichloride; zinc; In carbon disulfide;

upstream raw materials:

7-bromo-3,4-dihydro-2H-naphthalen-1-one

7-bromo-1,2,3,4-tetrahydronaphthalen-1-ol

4-(4-bromophenyl)butanoic acid

Downstream raw materials:

1,2-dihydro-6-methylnaphthalene

7-bromo-1,2-epoxy-1,2,3,4-tetrahydronaphthalene

(1S,2S)-1-amino-7-bromo-1,2,3,4-tetrahydronaphthalen-2-ol (2S,3S)-2,3-bis(4-methylbenzoyloxy)succinate

(+/-)-1-amino-7-bromo-1,2,3,4-tetrahydronaphthalene

Refernces

• 1、 Trenner, Johanna,Depken, Christian,Weber, Thomas,Breder, Alexander. "Direct oxidative allylic and vinylic amination of alkenes through selenium catalysis". . p. 8952 - 8956. Retrieved 2013/09/02.
• 2、 -. "Piperazine compounds". Page/Page column 7. . Retrieved 2008/06/13.