TMS-GLYCEROL

Base Information

• Chemical Name: TMS-GLYCEROL
• CAS No.: 6787-10-6
• Molecular Formula: C12H32O3Si3
• Molecular Weight: 308.641
• Hs Code.: 2931900090
• Mol file: 6787-10-6.mol

Synonyms:1,2,3-tris-(trimethylsilanyloxy)-propane;2,2,8,8-Tetramethyl-5-[(trimethylsilyl)oxy]-3,7-dioxa-2,8-disilanonane;3,7-Dioxa-2,8-disilanonane, 2,2,8,8-tetramethyl-5-(trimethylsiloxy)-;3,7-Dioxa-2,8-disilanonane, 2,2,8,8-tetramethyl-5-[(trimethylsilyl)oxy]-;Glycerol, tris(trimethylsilyl) ether;Glycerol, tri-TMS derivative;tms-glycerol;Trimethylsilyl ether of glycerol

Chemical Property of TMS-GLYCEROL

Chemical Property:

• PSA: 27.69000
• LogP: 3.90950
• Storage Temp.: 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TMS-GLYCEROL

There total 8 articles about TMS-GLYCEROL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → 1,2,3-tris-trimethylsilanyloxy-propane (6787-10-6)

Guidance literature:

With SBA-15-supported cobalt(II) nanocatalyst; In neat (no solvent); at 20 ℃; for 1.5h;

DOI:10.1002/cbdv.201200071

Reference yield: 85.0%

trimethylsilyl cyanide (7677-24-9) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → 1,2,3-tris-trimethylsilanyloxy-propane (6787-10-6)

Guidance literature:

With zirconium hydroxide; sulfuric acid; at 20 ℃; for 0.0833333h; Neat (no solvent); Inert atmosphere;

DOI:10.1080/00397911.2010.497591

Reference yield: 78.0%

chloro-trimethyl-silane (75-77-4) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → 1,2,3-tris-trimethylsilanyloxy-propane (6787-10-6)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 5h;

DOI:10.1016/j.tetasy.2005.01.034

upstream raw materials:

chloro-trimethyl-silane

glycerol

hexamethyldisilathiane

1-(Trimethylsilyl)imidazole

Downstream raw materials:

C₁₆H₂₇O₆PSi₂

C₁₆H₂₇O₆PSi₂

1,2,3-tribromopropane

Refernces

• 1、 Rajabi, Fatemeh,Luque, Rafael,Serrano-Ruiz, Juan Carlos. "Efficient room-temperature O-silylation of alcohols using a SBA-15-supported cobalt(II) nanocatalyst". . p. 1823 - 1828. Retrieved 2012/10/29.
• 2、 Rodríguez-Sánchez,Hernández-Hernández,Ruiz-Matute,Sanz. "A derivatization procedure for the simultaneous analysis of iminosugars and other low molecular weight carbohydrates by GC-MS in mulberry (Morus sp.)". experimental part. p. 353 - 359. Retrieved 2011/09/12.