2,2,2-TRICHLOROETHYL LAURATE

Base Information

• Chemical Name: 2,2,2-TRICHLOROETHYL LAURATE
• CAS No.: 71071-51-7
• Molecular Formula: C14H25Cl3O2
• Molecular Weight: 331.71
• Mol file: 71071-51-7.mol

Synonyms:2,2,2-TRICHLOROETHYL LAURATE

Chemical Property of 2,2,2-TRICHLOROETHYL LAURATE

Chemical Property:

• Refractive Index: n20/D 1.461
• PSA: 26.30000
• LogP: 5.82070

Purity/Quality:

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2,2-TRICHLOROETHYL LAURATE

There total 1 articles about 2,2,2-TRICHLOROETHYL LAURATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

lauric acid (143-07-7) + 1,1,1-trichloroethanol (115-20-8) → 2,2,2-Trichloroethyl dodecanoate (71071-51-7)

Guidance literature:

lauric acid; With thionyl chloride; for 3h;

1,1,1-trichloroethanol; With triethylamine; In dichloromethane; at 20 ℃; for 8h; Further stages.;

DOI:10.1021/ol027139u

Reference yield: 95.0%

2,2,2-Trichloroethyl dodecanoate (71071-51-7) → 2-chloroethyl dodecanoate (64919-15-9)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; for 2.5h; Heating;

DOI:10.1021/ol027139u

Reference yield: 92.0%

2,2,2-Trichloroethyl dodecanoate (71071-51-7) → lauric acid (143-07-7)

Guidance literature:

With sodium tetrahydroborate; selenium; In N,N-dimethyl-formamide; at 40 - 50 ℃; for 1h;

DOI:10.1055/s-1989-27362

upstream raw materials:

lauric acid

1,1,1-trichloroethanol

Downstream raw materials:

6-O-lauroyl-D-glucopyranose

lauric acid

D-glucono-1,4-lactone

2-chloroethyl dodecanoate

Refernces

• 1、 Masaki, Yukio,Tanaka, Nobuyuki,Miura, Tsuyoshi. "Mild esterification and transesterification of carboxylic acids catalyzed by tetracyanoethylene and dicyanoketene dimethyl acetal". . p. 55 - 56. Retrieved 2007/10/03.