Methyl 2,6-dimethylbenzoate

Base Information

• Chemical Name: Methyl 2,6-dimethylbenzoate
• CAS No.: 14920-81-1
• Molecular Formula: C10H12O2
• Molecular Weight: 164.204
• Hs Code.: 2916399090
• Mol file: 14920-81-1.mol

Synonyms:2,6-Dimethylbenzoic acid methyl ester;

Chemical Property of Methyl 2,6-dimethylbenzoate

Chemical Property:

• Vapor Pressure: 0.146mmHg at 25°C
• Refractive Index: 1.508
• Boiling Point: 215.7 °C at 760 mmHg
• Flash Point: 87.3 °C
• PSA: 26.30000
• Density: 1.027 g/cm³
• LogP: 2.09000
• Storage Temp.: Room temperature.

Purity/Quality:

98%min ^*data from raw suppliers

Methyl2,6-dimethylbenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 2,6-dimethylbenzoate

There total 24 articles about Methyl 2,6-dimethylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,6-dimethylbenzoic acid (632-46-2) + dimethyl sulfate (77-78-1) → methyl 2,6-dimethylbenzoate (14920-81-1)

Guidance literature:

With potassium carbonate; In acetone; at 20 ℃;

Reference yield: 97.0%

2,6-dimethylbenzoic acid (632-46-2) + methyl iodide (74-88-4) → methyl 2,6-dimethylbenzoate (14920-81-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1055/s-0037-1611744

Reference yield: 93.0%

2,6-dimethylbenzoic acid (632-46-2) + carbonic acid dimethyl ester (616-38-6) → methyl 2,6-dimethylbenzoate (14920-81-1)

Guidance literature:

With tributyl-amine; In N,N-dimethyl-formamide; at 285 ℃; for 0.05h; under 112511 Torr;

DOI:10.1039/c2gc36226k

upstream raw materials:

diazomethane

2,6-dimethylbenzoic acid

methanol

dimethyl sulfate

Downstream raw materials:

7-methyl-3H-isobenzofuran-1-one

2,6-dimethylbenzoic acid

methyl 4-hydroxy-2,6-dimethylbenzoate

Refernces

• 1、 Bender,Chen. "-". . p. 30,32. Retrieved 1963.
• 2、 Tsaconas, Michael,Prager, Rolf H.,Millan, David S.. "Intramolecular rearrangements of but-3-enoic esters". . p. 435 - 437. Retrieved 2000.
• 3、 O'Brien, Connor J.,Nicewicz, David A.. "Milled Dry Ice as a C1 Source for the Carboxylation of Aryl Halides". supporting information. p. 814 - 816. Retrieved 2021/03/01.
• 4、 -. "APELIN RECEPTOR AGONISTS AND METHODS OF USE THEREOF". Paragraph 0478-0479. . Retrieved 2019/02/25.