C₂₃H₂₀Cl₂N₆

Base Information

• Chemical Name: C₂₃H₂₀Cl₂N₆
• CAS No.: 1296644-77-3
• Molecular Formula: C₂₃H₂₀Cl₂N₆
• Molecular Weight: 451.358
• Mol file: 1296644-77-3.mol

Synonyms:

Chemical Property of C₂₃H₂₀Cl₂N₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₂₀Cl₂N₆

There total 3 articles about C₂₃H₂₀Cl₂N₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-bromopyridazin-3-amine (88497-27-2) + C19H18BCl2N3O2 (1042443-53-7) → C23H20Cl2N6 (1296644-77-3)

Guidance literature:

With sodium carbonate; In ethanol; water; toluene; at 100 ℃;

DOI:10.1016/j.bmcl.2011.01.125

Reference yield:

C12H14ClNS (1296644-90-0) → C23H20Cl2N6 (1296644-77-3)

Guidance literature:

Multi-step reaction with 3 steps

1: trimethylsilyl trifluoromethanesulfonate; silver trifluoromethanesulfonate / toluene / 100 °C

2: n-butyllithium; Triisopropyl borate / tetrahydrofuran / -78 - 20 °C

3: sodium carbonate / ethanol; water; toluene / 100 °C

With n-butyllithium; Triisopropyl borate; trimethylsilyl trifluoromethanesulfonate; silver trifluoromethanesulfonate; sodium carbonate; In tetrahydrofuran; ethanol; water; toluene; 3: Suzuki coupling;

DOI:10.1016/j.bmcl.2011.01.125

Reference yield:

4-bromo-2-chlorobenzohydrazide (206559-39-9) → C23H20Cl2N6 (1296644-77-3)

Guidance literature:

Multi-step reaction with 3 steps

1: trimethylsilyl trifluoromethanesulfonate; silver trifluoromethanesulfonate / toluene / 100 °C

2: n-butyllithium; Triisopropyl borate / tetrahydrofuran / -78 - 20 °C

3: sodium carbonate / ethanol; water; toluene / 100 °C

With n-butyllithium; Triisopropyl borate; trimethylsilyl trifluoromethanesulfonate; silver trifluoromethanesulfonate; sodium carbonate; In tetrahydrofuran; ethanol; water; toluene; 3: Suzuki coupling;

DOI:10.1016/j.bmcl.2011.01.125

upstream raw materials:

6-bromopyridazin-3-amine

C₁₉H₁₈BCl₂N₃O₂

C₁₂H₁₄ClNS

4-bromo-2-chlorobenzohydrazide

Refernces