1-Ethoxy-2-iodoethane

Base Information

• Chemical Name: 1-Ethoxy-2-iodoethane
• CAS No.: 6069-06-3
• Molecular Formula: C4H9 I O
• Molecular Weight: 200.019
• European Community (EC) Number: 822-084-5
• Nikkaji Number: J1.822.388K
• Mol file: 6069-06-3.mol

Synonyms:1-ethoxy-2-iodoethane;6069-06-3;1-ethoxy-2-iodo-ethane;SCHEMBL1126616;YZWJRUFHOBINIK-UHFFFAOYSA-N;AKOS014116120;EN300-185518;A1-04428

Chemical Property of 1-Ethoxy-2-iodoethane

Chemical Property:

• Vapor Pressure: 2.79E-15mmHg at 25°C
• Boiling Point: 619.6°C at 760 mmHg
• Flash Point: 328.5°C
• Density: 1.34g/cm³
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 199.96981
• Heavy Atom Count: 6
• Complexity: 23.5

Purity/Quality:

98.5% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOCCI

Technology Process of 1-Ethoxy-2-iodoethane

There total 6 articles about 1-Ethoxy-2-iodoethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

2-ethoxyethyl p-toluenesulfonate (17178-11-9) → 2-iodoethyl ethyl ether (6069-06-3)

Guidance literature:

With sodium iodide; In acetone; Reflux;

Reference yield:

→ 2-iodoethyl ethyl ether (6069-06-3)

Guidance literature:

With acetone; sodium iodide; at 25 ℃;

DOI:10.1021/jo01165a017

Reference yield:

2-chloroethyl ethyl ether (628-34-2) → 2-iodoethyl ethyl ether (6069-06-3)

Guidance literature:

With acetone; sodium iodide;

upstream raw materials:

ethanol

1,2-Diiodoethane

2-chloroethyl ethyl ether

2-ethoxy-ethanol

Downstream raw materials:

acetic acid-[4-(2-ethoxy-ethoxy)-anilide]

ethyl vinyl ether

3-(ethoxy)propionitrile

2-chloroethyl ethyl ether

Refernces

• 1、 Iranpoor,Firouzabadi,Aghapour,Vaez zadeh. "Triphenylphosphine/2,3-dichloro-5,6-dicyanobenzoquinone as a new, selective and neutral system for the facile conversion of alcohols, thiols and selenols to alkyl halides in the presence of halide ions". . p. 8689 - 8693. Retrieved 2007/10/03.
• 2、 Thanei Wyss,Waser. "Synthesis of reversible inhibitors of acetylcholinesterase (EC 3.1.1.7)". . p. 2198 - 2205. Retrieved 2007/10/02.