(R) -ginsenoside Rh1

Base Information

• Chemical Name: (R) -ginsenoside Rh1
• CAS No.: 80952-71-2
• Molecular Formula: C₃₆H₆₂O₉
• Molecular Weight: 638.883
• Mol file: 80952-71-2.mol

Synonyms:Dammarane,b-D-glucopyranoside deriv.;(20R)-Ginsenoside Rh1

Chemical Property of (R) -ginsenoside Rh1

Chemical Property:

• Vapor Pressure: 2.57E-26mmHg at 25°C
• Boiling Point: 755.1°C at 760 mmHg
• PKA: 12.91±0.70(Predicted)
• Flash Point: 410.5°C
• PSA: 160.07000
• Density: 1.23g/cm³
• LogP: 3.29560
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%Min ^*data from raw suppliers

20(R)?-?GinsenosideRh1 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 20(R)?-?Ginsenoside Rh1 is a ginsenoside derivative, obtained from the ginseng plant and displays anti-cancer activity in human breast cancer cell lines.

Technology Process of (R) -ginsenoside Rh1

There total 12 articles about (R) -ginsenoside Rh1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

C69H86O14 (1462261-07-9) → ginsenoside Rh1 (80952-71-2,63223-86-9)

Guidance literature:

With potassium hydroxide; In methanol; at 20 ℃;

DOI:10.1039/c3sc51479j

Reference yield:

ginsenoside Rf (52286-58-5,97276-51-2) → β-D-glucose (492-61-5) + ginsenoside Rh1 (80952-71-2,63223-86-9)

Guidance literature:

With Penicillium decumbens naringinase; enzymatic hydrolysis;

DOI:10.1055/s-2003-38476

Reference yield:

ginsenoside-Rg1 (22427-39-0) → β-D-glucose (492-61-5) + ginsenoside Rh1 (80952-71-2,63223-86-9)

Guidance literature:

With Penicillium sp. lactase; enzymatic hydrolysis;

DOI:10.1055/s-2003-38476

upstream raw materials:

ginsenoside Rg₁

ginsenoside Rf

ginsenoside-Rg₁

ginsenoside Re

Downstream raw materials:

20S-protopanaxatriol

6α-O-β-D-glucopyranosyl-(20S,24R)-epoxydammarane-3β,12β,25-triol

Refernces

• 1、 Zhang, Rui,Li, Na,Xu, Shujing,Han, Xiaowei,Li, Chunyan,Wei, Xin,Liu, Yu,Tu, Tao,Tang, Xianghua,Zhou, Junpei,Huang, Zunxi. "Glycoside Hydrolase Family 39 β-Xylosidases Exhibit β-1,2-Xylosidase Activity for Transformation of Notoginsenosides: A New EC Subsubclass". . p. 3220 - 3228. Retrieved 2019/03/26.
• 2、 Pei, Jianjun,Wu, Tao,Yao, Tao,Zhao, Linguo,Ding, Gang,Wang, Zhenzhong,Xiao, Wei. "Biotransformation of Ginsenosides Re and Rg1 into Rg2 and Rh1 by Thermostable β-Glucosidase from Thermotoga thermarum". . p. 472 - 477. Retrieved 2017/08/30.