Tetrabutylphosphonium hydroxide

Base Information

• Chemical Name: Tetrabutylphosphonium hydroxide
• CAS No.: 14518-69-5
• Deprecated CAS: 713543-17-0,2303978-29-0
• Molecular Formula: C16H37OP
• Molecular Weight: 276.443
• Hs Code.: 29319019
• European Community (EC) Number: 238-528-0
• DSSTox Substance ID: DTXSID70884758
• Mol file: 14518-69-5.mol

Synonyms:Tetrabutylphosphonium hydroxide;14518-69-5;tetrabutylphosphanium;hydroxide;Phosphonium, tetrabutyl-, hydroxide (1:1);EINECS 238-528-0;TBPH solution;SCHEMBL108027;C16H36P.HO;DTXSID70884758;C16-H36-P.H-O;MFCD00068456;AKOS015950702;FT-0769999;T2571;J-008067

Chemical Property of Tetrabutylphosphonium hydroxide

Chemical Property:

• Appearance/Colour: COLORLESS TO LIGHT YELLOW LIQUID
• Refractive Index: n20/D 1.412
• PSA: 36.65000
• Density: 0.989 g/mL at 25 °C
• LogP: 6.02760
• Water Solubility.: Miscible with water.
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 12
• Exact Mass: 276.25820280
• Heavy Atom Count: 18
• Complexity: 116

Purity/Quality:

99.9% ^*data from raw suppliers

Tetrabutylphosphonium Hydroxide (40% in Water) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Phosphorus Compounds
• Canonical SMILES: CCCC[P+](CCCC)(CCCC)CCCC.[OH-]
• Uses: Tetrabutylphosphonium Hydroxide (TBPH) is a quaternary phosphonium salt. It is an effective catalyst in a variety of reactions. It is a strong base that can be used as a strong organic base catalyst. Its basicity combined with its function as phase transfer catalyst makes it a versatile catalyst in many biphasic organic transitions used in the manufacture of polymers, pharmaceuticals, agrochemicals, flavors and fragrances. Also it finds use as (trans)esterification catalyst for the preparation of several monomers,polymers and a cleaning agent for printed circuit boards and semiconductor wafers. Applications: Glycidyl Ether Intermediates used in pharmaceutical applications. Chemicals for Polymer Applications. Tetrabutylphosphonium Hydroxide is a phase transfer catalyst for the etherification of thiosalicylic acid and analogs. Tetrabutylphosphonium Hydroxide is a pretreatment for rice husks that enhances enzymic and acid hydrolysis yields. Tetrabutylphosphonium Hydroxide is used in the synthesis of tetrabutylphosphonium carboxylate as a recyclable and highly selective catalysts for alcoholysis reaction of propylene oxide.

Technology Process of Tetrabutylphosphonium hydroxide

There total 2 articles about Tetrabutylphosphonium hydroxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tetrabutyl phosphonium bromide (3115-68-2) → tetra-n-butylphosphonium hydroxide (14518-69-5)

Guidance literature:

With Amberlite IRN-78; In methanol; water;

DOI:10.1016/j.molliq.2010.02.002

Reference yield:

tetra-n-butylphosphonium chloride (2304-30-5) → tetra-n-butylphosphonium hydroxide (14518-69-5)

Guidance literature:

With Amberlite IRA-402(OH);

DOI:10.1039/c7cc01796k

Reference yield: 100.0%

ibuprofen (15687-27-1,58560-75-1) + tetra-n-butylphosphonium hydroxide (14518-69-5) → tetrabutylphosphonium ibuprofenate (1234188-37-4)

Guidance literature:

In water; acetone; at 20 ℃; for 0.25h;

upstream raw materials:

tetrabutyl phosphonium bromide

tetra-n-butylphosphonium chloride

Downstream raw materials:

tetrabutylphosphonium benzoate

Tetrabutylphosphonium Benzene Sulfinate

tetra(n-butyl)phosphonium malonate

tetra-n-butylphosphonium acetate

Refernces

• 1、 Wei, Liang,Geng, Zeyu,Liu, Yantong,Lu, Ruizhong,Xu, Yifan,Liu, Chunjie,Xu, Yun. "Highly efficient and reversible H2S capture by mercapto carboxylic anion functionalized ionic liquids". . . Retrieved 2021/08/03.
• 2、 Kagimoto, Junko,Taguchi, Satomi,Fukumoto, Kenta,Ohno, Hiroyuki. "Hydrophobic and low-density amino acid ionic liquids". experimental part. p. 133 - 138. Retrieved 2010/11/18.