(2-Naphtyloxy)trimethylsilane

Base Information

• Chemical Name: (2-Naphtyloxy)trimethylsilane
• CAS No.: 18081-08-8
• Molecular Formula: C13H16OSi
• Molecular Weight: 216.355
• Hs Code.: 2931900090
• Mol file: 18081-08-8.mol

Synonyms:2-trimethylsiloxynaphthalene;2-naphthyl trimethylsilyl ether;

Chemical Property of (2-Naphtyloxy)trimethylsilane

Chemical Property:

• Melting Point: 69-72 °C
• Boiling Point: 98.2-101.0 °C(Press: 8 Torr)
• PSA: 9.23000
• Density: 1.000±0.06 g/cm3(Predicted)
• LogP: 4.05350

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-[(Trimethylsilyl)oxy]naphthalene is an intermediate in the synthesis of 2-Sulfamate-2-deoxy-1-α-(2-naphthyl)-glucopyranoside Sodium Salt (S789204), a derivative of Napthalene (N345600), an abundant polycyclic aromatic hydrocarbon that is persistent, bioaccumulative, toxic and found in tobacco smoke and urban air.

Technology Process of (2-Naphtyloxy)trimethylsilane

There total 10 articles about (2-Naphtyloxy)trimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) + β-naphthol (135-19-3) → 2-naphthyl trimethylsilyl ether (18081-08-8)

Guidance literature:

With SBA-15-supported cobalt(II) nanocatalyst; In neat (no solvent); at 20 ℃; for 1h;

DOI:10.1002/cbdv.201200071

Reference yield: 98.0%

β-naphthol (135-19-3) + lithium hexamethyldisilazane (4039-32-1) → 2-naphthyl trimethylsilyl ether (18081-08-8)

Guidance literature:

With N-chlorosaccharin; In neat (no solvent); at 20 ℃; for 0.25h;

DOI:10.1002/jccs.201300624

Reference yield: 90.0%

chloro-trimethyl-silane (75-77-4) + β-naphthol (135-19-3) → 2-naphthyl trimethylsilyl ether (18081-08-8)

Guidance literature:

With triethylamine; at 20 ℃; for 0.0833333h; Inert atmosphere;

DOI:10.1002/jccs.201300586

upstream raw materials:

chloro-trimethyl-silane

β-naphthol

N,N-bis(trimethylsilyl)acetamide

1,1,1,3,3,3-hexamethyl-disilazane

Downstream raw materials:

2-naphthyl benzoate

naphthalen-2-yl acetate

2-Methylnaphthalene

2-(2-methylphenyl)naphthalene

Refernces

• 1、 Mohammadiyan, Esmaeel,Ghafuri, Hossein,Kakanejadifard, Ali. "Synthesis and characterization of a bifunctional nanomagnetic solid acid catalyst (Fe3O4@CeO2/SO42?) and investigation of its efficiency in the protection process of alcohols and phenols via hexamethyldisilazane under solvent-free conditions". . p. 171 - 178. Retrieved 2018/09/12.
• 2、 Zolfigol, Mohammad Ali,Sajjadifar, Sami,Ghorbani-Choghamarani, Arash,Tami, Farzaneh. "Application of a novel nano-immobilization of ionic liquid on an MCM-41 system for trimethylsilylation of alcohols and phenols with hexamethyldisilazane". . p. 7093 - 7106. Retrieved 2018/08/17.