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Chemical Baike

Deprotection Reaction

The Dts protecting group is removable by reduction. Reduction of the Dts-protected cysteine can be achieved using a reducing agent like dithiothreitol (DTT) or tris(2-carboxyethyl)phosphine (TCEP). These reducing agents cleave the Dts group, revealing the free thiol group on the cysteine residue.

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