Discuss the in vivo experiments conducted to assess the local anesthetic properties of the synthesized compounds. Detail the animal model used (e.g., rats) and the methodology for evaluating sciatic nerve block activity. Provide the results, including dose-response curves and comparative analysis with lidocaine as a reference compound.
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Benzenamine, 2-(chloromethyl)-6-(trifluoromethyl)-, hydrochloride
Succinimide
HCl
