Interpret the results of the sciatic nerve block activity evaluation and molecular docking studies. Discuss the structure-activity relationships of the fluoro-substituted lidocaine analogs and their potential mechanisms of action. Compare the experimental findings with the existing literature on local anesthetics.
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Benzenamine, 2-(chloromethyl)-6-(trifluoromethyl)-, hydrochloride
Succinimide
HCl
Tetraethylammonium perchlorate
Butylamine
4
