Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Trimethylcolchicinic acid

Related Products

Hot Products

Name

Trimethylcolchicinic acid

EINECS N/A
CAS No. 3482-37-9 Density 1.32g/cm3
PSA 91.01000 LogP 3.09150
Solubility N/A Melting Point >230°C (dec.)
Formula C19H21 N O5 Boiling Point 629°Cat760mmHg
Molecular Weight 343.379 Flash Point 334.2°C
Transport Information N/A Appearance N/A
Safety Poison by intraperitoneal route. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also COLCHICINE. Risk Codes 20/21/22
Molecular Structure Molecular Structure of 3482-37-9 (TRIMETHYLCOLCHICINIC ACID) Hazard Symbols
Synonyms

Benzo[a]heptalen-9(5H)-one,7-amino-6,7-dihydro-10-hydroxy-1,2,3-trimethoxy-, (S)-; Colchiceine,N-deacetyl- (8CI); Colchicinic acid, O,O',O''-trimethyl- (6CI,7CI);Deacetylcolchiceine; Desacetylcolchiceine; N-Deacetylcolchiceine; NSC 36796;Trimethylcolchicinic acid

Article Data 15

Trimethylcolchicinic acid Chemical Properties

IUPAC Name: 7-Amino-10-hydroxy-1,2,3-trimethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one  
Molecular Formula: C19H21NO5
Molecular Weight: 343.41
Properties: yellow-green solid 
EINECS: 222-464-5
Density: 1.32g/cm3
Melting Point: >230°C (dec.)
Boiling Point: 629°C at 760mmHg
Flash Point: 334.2°C
Freely Rotating Bonds: 5
Polar Surface Area: 57.23 Å2
Index of Refraction: 1.628
Molar Refractivity: 92.35 cm3
Molar Volume: 260 cm3
Polarizability: 36.61× 10-24 cm3
Surface Tension: 59 dyne/cm
Enthalpy of Vaporization: 97.82 kJ/mol
Vapour Pressure: 1.09E-16 mmHg at 25°C 
Storage temperature: −20°C
The Cas Register Number of Trimethylcolchicinic acid is 3482-37-9.The chemical synonyms of Trimethylcolchicinic acid (CAS NO.3482-37-9) are Trimethylcolchicinic acid ; 7-Amino-6,7-dihydro-10-hydroxy-1,2,3-trimethoxy-benzo(a)heptalen-9(5h)-on ; Deacetylcholchiceine ; Desacetylcholchiceine ; N-Deacetyl-colchicein ; Trimethyl-colchicinicaci ; N-Deacetylcolchiceine ; (S)-7-Amino-6,7-dihydro-10-hydroxy-1,2,3-trimethoxybenzo[a]heptalen-9(5H)-one .Product categories of Trimethylcolchicinic acid (CAS NO.3482-37-9) are All inhibitors ; Inhibitors ; Alkaloids forensic and veterinary standards ; Chemical structure; Drugs of abuse ; Drugs and Metabolites ; Neat compounds drugs of abuse ; Others alphabetic ; TP - TZ  .The molecular structure of Trimethylcolchicinic acid (CAS NO.3482-37-9) is.

Trimethylcolchicinic acid Uses

 Trimethylcolchicinic acid (CAS NO.3482-37-9) is used as  an antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization.

Trimethylcolchicinic acid Toxicity Data With Reference

1.    

oms-mus-par 200 mg/kg

    CANCAR    Cancer. 3 (1950),134.
2.    

spm-mus-par 200 mg/kg

    CANCAR    Cancer. 2 (1950),134.
3.    

ipr-mus LD50:200 mg/kg

    CANCAR    Cancer. 3 (1950),124.

Trimethylcolchicinic acid Safety Profile

Poison by intraperitoneal route. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also COLCHICINE.
Hazard Codes: HarmfulXn
Risk Statements: 20/21/22 
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 36 
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS: GH0960000

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 3482-37-9