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| CAS No.: | 56-45-1 |
|---|---|
| Name: | L-Serine |
| Article Data: | 200 |
| Molecular Structure: | |
|
|
|
| Formula: | C3H7NO3 |
| Molecular Weight: | 105.093 |
| Synonyms: | (S)-alpha-Amino-beta-hydroxypropionic acid;Propanoic acid, 2-amino-3-hydroxy-, (S)-;(2S)-2-amino-3-hydroxypropanoic acid;L-2-Amino-3-hydroxypropionic acid;L-(-)-serine;beta-Hydroxyalanine;2-Amino-3-hydroxypropanoic acid, (S)-;alpha-Amino-beta-hydroxypropionic acid; |
| EINECS: | 200-274-3 |
| Density: | 1.416 g/cm3 |
| Melting Point: | 222ºC |
| Boiling Point: | 394.822 °C at 760 mmHg |
| Flash Point: | 192.582 °C |
| Solubility: | 250 g/L (20 ºC) |
| Appearance: | White crystalline powder |
| Hazard Symbols: |
 Xi
|
| Risk Codes: | 36/37/38 |
| Safety: | 24/25-36-26 |
| PSA: | 83.55000 |
| LogP: | -0.90910 |
- 81281-59-67-Benzylideneaminotheophylline
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| Conditions | Yield |
|---|---|
| With Nafion H; trifluoroacetic acid for 3h; | 100% |
| With Nafion H; dimethylsulfide; 3-methyl-phenol; trifluoroacetic acid for 3h; Product distribution; other deprotection agents; | 100% |
| With dimethylsulfide; trifluorormethanesulfonic acid; 30 (v/v); trifluoroacetic acid at 0℃; for 4h; Yield given; |
- 23680-31-1
BOC-O-benzyl-L-serine
- 56-45-1
L-serin
| Conditions | Yield |
|---|---|
| With dimethylsulfide; hydrogen fluoride at 0℃; for 2h; Product distribution; Var.: HF in anisole; | 100% |
| With hydrogen; sodium dodecyl-sulfate; Lindlar's catalyst In methanol; water under 3.4 Torr; Yield given; |
| Conditions | Yield |
|---|---|
| With palladium/alumina; hydrogen at 70℃; neat (no solvent); | 100% |
| With hydrogen; hydroxyapatite-bound Pd In methanol at 40℃; for 3h; | 92% |
| With ethylenediaminetetraacetic acid; phenylmethylsulphonyl fluoride; water In aq. phosphate buffer at 30℃; Kinetics; Reagent/catalyst; Microbiological reaction; Enzymatic reaction; |
- 56-45-1
L-serin
| Conditions | Yield |
|---|---|
| With ruthenium nanoparticles dispersed in a polyvinylpyrrolidone matrix; amberlyst A-21 In methanol; dichloromethane | 99% |
| Conditions | Yield |
|---|---|
| With trimethylsilyl trifluoromethanesulfonate; diphenyl sulfide In trifluoroacetic acid at 0℃; for 0.5h; Product distribution; New peptide deprotection procedure: hard-soft acid-base concept; the role of soft bases (thioanisole, dimethylsulfide, diphenylsulfide) employed; effect of var. hard bases; var. reaction cond.; | 97.8% |
| With methyl-phenyl-thioether; trimethyl(2,4,6-trimethylphenoxy)silane In trifluoroacetic acid at 22℃; for 1h; | 93.5% |
- 111-26-2
hexan-1-amine
- 78641-68-6
(S)-2-(3,5-Dinitro-4-oxo-4H-pyridin-1-yl)-3-hydroxy-propionic acid
A
- 56-45-1
L-serin
B
- 74197-48-1
1-hexyl-3,5-dinitro-4-pyridone
| Conditions | Yield |
|---|---|
| In pyridine Product distribution; | A 90.9% B n/a |
- 30406-21-4
N-carbamyl-DL-serine
- 56-45-1
L-serin
| Conditions | Yield |
|---|---|
| With NH4Cl-NH4OH buffer pH 8.5; nickel dichloride at 60℃; for 24h; N-carbamyl-L-amino acid aminohydrolase; | 86% |
- 56-45-1
L-serin
| Conditions | Yield |
|---|---|
| With hydrogenchloride In methanol; water at 20℃; for 0.5h; Inert atmosphere; | 85% |
- 56-45-1
L-serin
| Conditions | Yield |
|---|---|
| With perchloric acid at 80℃; for 0.5h; | 67% |
- 56-45-1
L-serin
| Conditions | Yield |
|---|---|
| With sodium formate; ammonium chloride; NADH In aq. phosphate buffer at 25℃; for 6h; pH=8.0; Kinetics; Reagent/catalyst; Green chemistry; Enzymatic reaction; | 36.6% |
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Chemistry
Molecular Structure:
Molecular Formula: C3H7NO3
Molecular Weight: 105.0926
IUPAC Name: (2S)-2-Amino-3-hydroxypropanoic acid
Synonyms of L-serine (CAS NO.56-45-1): (S)-2-Amino-3-hydroxypropanoic acid ; (S)-Serine ; 2-Amino-3-hydroxypropanoic acid ; 2-Amino-3-hydroxypropanoic acid, (S)- ; 4-04-00-03118 (Beilstein Handbook Reference) ; BRN 1721404 ; EINECS 200-274-3 ; HSDB 680 ; NSC 118365 ; Propanoic acid, 2-amino-3-hydroxy-, (S)- ; SER (IUPAC abbrev) ; Serene ; Serina ; Serina [Spanish] ; Serine ; Serine (VAN) ; Serinum ; Serinum [Latin] ; UNII-452VLY9402 ; alpha-Amino-beta-hydroxypropionic acid ; beta-Hydroxyalanine
CAS NO: 56-45-1
Classification Code: Amino acid ; Mutation data
Melting point: 222 °C
Water Solubility: 250 g/L (20 °C)
Alpha: 15.2 o (c=10, 2N HCl)
Storage temp.: Store at 0-5
Solubility H2O: 50 mg/mL
form: powder
Sublimation: 150 °C
Density: 1.415 g/cm3
Flash Point: 192.6 °C
Index of Refraction: 1.519
Surface Tension: 72.2 dyne/cm
Enthalpy of Vaporization: 74.56 kJ/mol
Boiling Point: 394.8 °C at 760 mmHg
Vapour Pressure: 7.17E-08 mmHg at 25 °C
Appearance of L-serine (CAS NO.56-45-1): White crystalline powder
Production
Racemic serine can be prepared from METHYL ACRYLATE via several steps
Safety Profile
Hazard Codes of L-serine (CAS NO.56-45-1): 
Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36-26
S24/25: Avoid contact with skin and eyes.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
WGK Germany: 3
F: 3
Specification
L-serine (CAS NO.56-45-1) is Stable, and incompatible with strong oxidizing agents. It is stable under normal temperatures and pressures. It should avoid incompatible materials, light, exposure to moist air or water, and it's incompatibilities with strong oxidizing agents. Its hazardous decomposition products are nitrogen oxides, carbon monoxide and carbon dioxide.