1000313-19-8

Basic information

• Product Name: N-(4-methanesulfonylamino-2-sulfamoylphenyl)malonamic acid methyl ester
• Synonyms: N-(4-methanesulfonylamino-2-sulfamoylphenyl)malonamic acid methyl ester
• CAS NO: 1000313-19-8
• Molecular Weight: 365.388
• Mol File: 1000313-19-8.mol
• Article Data: 6

Chemical Properties

• Density: 1.599±0.06 g/cm3(Predicted)
• CAS DataBase Reference: N-(4-methanesulfonylamino-2-sulfamoylphenyl)malonamic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methanesulfonylamino-2-sulfamoylphenyl)malonamic acid methyl ester(1000313-19-8)
• EPA Substance Registry System: N-(4-methanesulfonylamino-2-sulfamoylphenyl)malonamic acid methyl ester(1000313-19-8)

Safety Data

• Hazardous Substances Data: 1000313-19-8(Hazardous Substances Data)

Upstream product

• 691361-76-9 2-amino-5-(methanesulfonylamino)benzenesulfonamide 
• 37517-81-0 3-chloro-3-oxopropanoic acid methyl ester 
• 96-72-0 2-chloro-5-nitrobenzenesulfonamide 
• 20896-44-0 2,5-diaminobenzenesulfonamide 
• 54734-85-9 2-amino-5-nitrobenzenesulfonamide 
• 96-75-3 2-amino-5-nitro-benzenesulfonic acid 
• 1000313-17-6 2-benzylamino-5-nitro-benzenesulfonamide 
• 4533-95-3 5-nitro-2-chlorobenzenesulfonyl chloride 
• 1071519-76-0 2,5-diamino-benzenesulfonamide methanesulfonate 
• 96-73-1 2-chloro-5-nitro-benzenesulfonic acid 
• 1618673-13-4 N-(4-nitro-2-sulfamoylphenyl)malonamic acid methyl ester 
• 1618673-18-9 N-(4-amino-2-sulfamoylphenyl)malonamic acid methyl ester 
• 124-63-0 methanesulfonyl chloride 
• 20628-33-5 2-Amino-5-nitro-benzolsulfonylchlorid 

Downstream Products

• 1071517-39-9 N-{3-[(1R,2S,7R,8S)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.0(2,7)]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}methanesulfonamide 
• 1071520-44-9 (1S,2R,3S,4R)-3-{(4-fluorobenzyl)-[2-(7-methanesulfonylamino-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-3-yl)acetyl]amino}bicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester 
• 1071519-59-9 N-{3-[(1R,2S,7R,8S)-3-(4-fluorobenzyl)-6-hydroxy-4-oxo-3-azatricyclo[6.2.1.02,7]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}methanesulfonamide L-arginine salt 
• 1071519-62-4 N-{3-[(1R,2S,7R,8S)-3-(4-fluorobenzyl)-6-hydroxy-4-oxo-3-azatricyclo[6.2.1.02,7]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}methanesulfonamide L-lysine salt 
• 1071519-66-8 N-{3-[(1R,2S,7R,8S)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.0(2,7)]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}methanesulfonamide sodium salt 
• 1071519-68-0 N-{3-[(1R,2S,7R,8S)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.0(2,7)]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}methanesulfonamide potassium salt 
• 1071517-44-6 N-{3-[(1S,2R,7S,8R)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.02,7]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide 
• 1071518-93-8 N-{3-[(2S,7R)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.2.02,7]dodec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide 
• 1071517-31-1 N-{3-[(1S,2S,7R,8R)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.02,7]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide 
• 1071517-35-5 N-{3-[(1R,2R,7S,8S)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.02,7]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide 
• 1071517-60-6 N-{3-[(1S,2R,7S,8R)-3-(4-fluoro-3-methylbenzyl)-6-hydroxy-4-oxo-11-oxa-3-aza-tricyclo[6.2.1.02,7]undec-5-en-5-yl]-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}methanesulfonamide 
• 1071517-70-8 N-{3-[(1S,2R,7S,8R)-3-(4-fluorobenzyl)-6-hydroxy-4-oxo-11-oxa-3-aza-tricyclo[6.2.1.02,7]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}methanesulfonamide 
• 1071517-74-2 N-{3-[(1R,2S,7R,8S)-3-(4-fluoro-3-methylbenzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.02,7]undec-5-en-5-yl]-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}methanesulfonamide 
• 1071517-76-4 N-{3-[(1R,2S,7R,8S)-3-(3,4-difluorobenzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.02,7]undec-5-en-5-yl]-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}methanesulfonamide 

Relevant articles and documents

A NOVEL PROCESS FOR THE PREPARATION OF N-(4-NITRO-2-SULFAMOYL-PHENYL)-MALONAMIC ACID METHYL ESTER AND N-(4-AMINO-2-SULFAMOYL-PHENYL)-MALONAMIC ACID METHYL ESTER

The present invention provides a novel method for preparing compounds N-(4-nitro-2-sulfamoyl-phenyl)-malonamic acid methyl ester and N-(4-amino-2-sulfamoyl-phenyl)-malonamic acid methyl ester, which are novel intermediates for preparing a key intermediate

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5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS

The invention is directed to 5,6-dihydro-lH-pyridin-2-one compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.