101566-00-1

Basic information

• Product Name: (2-METHYL-3-NITRO-PHENYL)-ACETYL CHLORIDE
• Synonyms: (2-METHYL-3-NITRO-PHENYL)-ACETYL CHLORIDE;2-(2-methyl-3-nitrophenyl)acetyl chloride
• CAS NO: 101566-00-1
• Molecular Formula: C₉H₈ClNO₃
• Molecular Weight: 213.62
• Mol File: 101566-00-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2-METHYL-3-NITRO-PHENYL)-ACETYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (2-METHYL-3-NITRO-PHENYL)-ACETYL CHLORIDE(101566-00-1)
• EPA Substance Registry System: (2-METHYL-3-NITRO-PHENYL)-ACETYL CHLORIDE(101566-00-1)

Safety Data

• Hazardous Substances Data: 101566-00-1(Hazardous Substances Data)

Upstream product

• 1975-50-4 2-methyl-3-nitrobenzic acid 
• 60468-54-4 1-chloromethyl-2-methyl-3-nitro-benzene 
• 23876-14-4 3-nitro-2-methylphenylacetonitrile 
• 23876-13-3 (2-methyl-3-nitrophenyl)methanol 
• 23876-15-5 2-(3-nitro-2-methylphenyl)acetic acid 

Downstream Products

• 91374-22-0 2-(2-methyl-3-nitro-phenyl)-N,N-di-n-propylacetamide 
• 91374-25-3 <2-nitro-6-<2-(N,N-di-n-propylamino)ethyl>phenyl>acetic acid hydrochloride 
• 97351-95-6 <2-nitro-6-<2-(N,N-di-n-propylamino)ethyl>phenyl>pyruvic acid 
• 720656-64-4 2-nitro-6-<2-(di-n-propylamino)ethyl>phenylacetic acid 
• 91374-21-9 Ropinirole 
• 91374-23-1 1-(2-dipropylaminoethyl)-2-methyl-3-nitrobenzene 
• 101566-02-3 N-(4-methoxyphenethyl)-N-(2-methyl-3-nitrophenethyl)-N-n-propylamine 
• 748747-23-1 2-nitro-6-<2-(N-benzyl-N-propylamino)ethyl>phenylacetic acid 
• 735245-67-7 4-<2-(N-benzyl-N-propylamino)ethyl>-2-indolone 
• 763060-96-4 N-benzyl-N-propyl-2-(2-methyl-3-nitrophenyl)ethylamine 
• 173990-72-2 ethyl 2-nitro-6-<2-(N-benzy;-N-propylaminoethyl)phenyl>pyruvate 
• 777831-40-0 2-nitro-6-<2-(N-benzyl-N-propylaminoethyl)>phenylpyruvic acid 
• 172328-06-2 E conformation of N-benzyl,N-n-propyl (2-methyl-3-nitrophenyl)acetamide 

Relevant articles and documents

Catalytic Direct Cyanomethylenation of C(sp3)–H Bonds via a One-Step Double C–C Bond Formation

An elegant and catalytic procedure for the one-step cyanomethylenation of C(sp3)–H bonds adjacent to benzazoles and ketones is described herein using DMF as a C-1 unit and TMSCN as the cyanide source. The copper-mediated reaction between DMF an

Synthesis of 4-N,N-dialkylaminoethyl-2-indolones as potential dopamine agonists

A set of fourteen 4-ethyl>-2-indolone analogues of dopamine were synthesized in 15 steps and evaluated for their affinities towards the D2 receptor using sulpiride or spiperone as radioligands.Six analogues displayed D2 agonist activities comparable (Ki = 450 - 650 nM) to Ropinirole or SK and F 101468.The functionalized amino side chain introduced in the 4-position can be used to modulate the lipophlicity of the analogues without significantly affecting D2 activity. - Keywords: lactam; indolone; rigid dopamine analogue; D2 receptor binding

4--2(3H)-indolone: A Prejunctional Dopamine Receptor Agonist

4--2(3H)-indolone (1c) (SK and F 101468) is a potent and selective prejunctional dopamine receptor agonist.It caused a dose-related inhibition of the constrictor response to electrical stimulation in the isolated perfused rabbit ear artery (EC50 = 100 nM), and this response was antagonized by (S)-sulpiride (KB = 7 nM).Compound 1c did not stimulate or block dopamine-sensitive adenylate cyclase and did not produce stimulation of the central nervous system in rats.It was prepared from (2-methyl-3-nitrophenyl)acetic acid in a multistep sequence based on the Reissert indole synthesis.