735245-67-7

Basic information

• Product Name: 4-<2-(N-benzyl-N-propylamino)ethyl>-2-indolone
• Synonyms: 4-<2-(N-benzyl-N-propylamino)ethyl>-2-indolone
• CAS NO: 735245-67-7
• Molecular Weight: 308.423
• Mol File: 735245-67-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-<2-(N-benzyl-N-propylamino)ethyl>-2-indolone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-<2-(N-benzyl-N-propylamino)ethyl>-2-indolone(735245-67-7)
• EPA Substance Registry System: 4-<2-(N-benzyl-N-propylamino)ethyl>-2-indolone(735245-67-7)

Safety Data

• Hazardous Substances Data: 735245-67-7(Hazardous Substances Data)

Upstream product

• 763060-96-4 N-benzyl-N-propyl-2-(2-methyl-3-nitrophenyl)ethylamine 
• 748747-23-1 2-nitro-6-<2-(N-benzyl-N-propylamino)ethyl>phenylacetic acid 
• 23876-15-5 2-(3-nitro-2-methylphenyl)acetic acid 
• 173990-72-2 ethyl 2-nitro-6-<2-(N-benzy;-N-propylaminoethyl)phenyl>pyruvate 
• 777831-40-0 2-nitro-6-<2-(N-benzyl-N-propylaminoethyl)>phenylpyruvic acid 
• 172328-06-2 E conformation of N-benzyl,N-n-propyl (2-methyl-3-nitrophenyl)acetamide 
• 101566-00-1 2-methyl-3-nitrophenylethanoyl chloride 

Relevant articles and documents

Synthesis of 4-N,N-dialkylaminoethyl-2-indolones as potential dopamine agonists

A set of fourteen 4-ethyl>-2-indolone analogues of dopamine were synthesized in 15 steps and evaluated for their affinities towards the D2 receptor using sulpiride or spiperone as radioligands.Six analogues displayed D2 agonist activities comparable (Ki = 450 - 650 nM) to Ropinirole or SK and F 101468.The functionalized amino side chain introduced in the 4-position can be used to modulate the lipophlicity of the analogues without significantly affecting D2 activity. - Keywords: lactam; indolone; rigid dopamine analogue; D2 receptor binding