10207-83-7Relevant articles and documents
Formal synthesis of (±)-Ambrox
Barco, Achille,Benetti, Simonetta,Bianchi, Anna,Casolari, Alberto,Guarneri, Mario,Pollini, Gian P.
, p. 8333 - 8338 (2007/10/02)
The immediate precursor of (±)-Ambrox 1 has been conveniently prepared in a seven-step sequence starting from the readily available methyl 2-oxo-5,5,8a-trimethyldecahydronaphthalene-1-carboxylate 2, in turn derived by stannic chloride-mediated cyclization of methyl 3-oxo-5-(2,6,6-trimethylcyclohexen-1-yl)pentanoate.
A formal synthesis of (±)-Ambrox
Snowden,Linder
, p. 4119 - 4120 (2007/10/02)
Bicyclic diol 6, a direct precursor of (±)-Ambrox ((±)-7), has been synthesised in four steps (35% yield) from the known bicyclic enone 2.
Triterpenoid Total Synthesis, I: Synthesis of Ambrein and Ambrox
Mori, Kenji,Tamura, Hiroshi
, p. 361 - 368 (2007/10/02)
The first total synthesis of (+)-ambrein (1), a triterpene alcohol isolated from ambergris, was achieved.Both the enantiomers of ambrox (2) were also synthesized.
