1026270-18-7

Basic information

• Product Name: 3,3-Bis-(2-fluoro-phenyl)-oxirane-2-carboxylic acid methyl ester
• Synonyms: 3,3-Bis-(2-fluoro-phenyl)-oxirane-2-carboxylic acid methyl ester
• CAS NO: 1026270-18-7
• Molecular Weight: 290.266
• Mol File: 1026270-18-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,3-Bis-(2-fluoro-phenyl)-oxirane-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-Bis-(2-fluoro-phenyl)-oxirane-2-carboxylic acid methyl ester(1026270-18-7)
• EPA Substance Registry System: 3,3-Bis-(2-fluoro-phenyl)-oxirane-2-carboxylic acid methyl ester(1026270-18-7)

Safety Data

• Hazardous Substances Data: 1026270-18-7(Hazardous Substances Data)

Upstream product

• 393-52-2 2-Fluorobenzoyl chloride 
• 1072-85-1 o-fluorobromobenzene 
• 342-23-4 bis(fluorophenyl)methanone 
• 96-34-4 methyl chloroacetate 

Downstream Products

• 1012079-84-3 2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(2-fluoro-phenyl)-3-methoxy-propionic acid methyl ester 

Relevant articles and documents

Discovery and optimization of a novel class of orally active nonpeptidic endothelin-A receptor antagonists

A novel class of endothelin-A receptor ligands was discovered by high-throughput screening. Lead structure optimization led to highly potent antagonists which can be synthesized in a short sequence. The compounds are endothelin-A-selective, are orally available, and show a long duration of action.