1049978-48-4Relevant articles and documents
High yielding microwave-assisted synthesis of tri-substituted 1,3,5-triazines using Pd-catalyzed aryl and heteroarylamination
Dao, Pascal,Garbay, Christiane,Chen, Huixiong
, p. 3856 - 3860 (2012)
A rapid and efficient Pd-catalyzed aryl and heteroarylamination under microwave irradiation has been developed for various tri-substituted triazines that can serve as versatile building blocks for both supramolecular and medicinal chemistry research. Particularly valuable features of this method included the short reaction time, good yield, and convenient operation.
Synthesis of novel diarylamino-1,3,5-triazine derivatives as FAK inhibitors with anti-angiogenic activity
Dao, Pascal,Jarray, Rafika,Le Coq, Johanne,Lietha, Daniel,Loukaci, Ali,Lepelletier, Yves,Hadj-Slimane, Réda,Garbay, Christiane,Raynaud, Fran?oise,Chen, Huixiong
, p. 4552 - 4556 (2013/08/23)
We report herein the synthesis of novel diarylamino-1,3,5-triazine derivatives as FAK (focal adhesion kinase) inhibitors and the evaluation of their anti-angiogenic activity on HUVEC cells. Generally, the effects of these compounds on endothelial cells co