107417-55-0

Basic information

• Product Name: 3-(1-piperidinomethyl)-anisole
• Synonyms: 3-(1-piperidinomethyl)-anisole
• CAS NO: 107417-55-0
• Molecular Weight: 205.3
• Mol File: 107417-55-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3-(1-piperidinomethyl)-anisole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1-piperidinomethyl)-anisole(107417-55-0)
• EPA Substance Registry System: 3-(1-piperidinomethyl)-anisole(107417-55-0)

Safety Data

• Hazardous Substances Data: 107417-55-0(Hazardous Substances Data)

Upstream product

• 2591-86-8 N-Formylpiperidine 
• 824-98-6 m-methoxybenzyl chloride 
• 110-89-4 piperidine 
• 1711-05-3 m-anisoyl chloride 
• 69001-09-8 (3-methoxyphenyl)(piperidin-1-yl)methanone 
• 6971-51-3 3-methoxybenzyl alcohol 
• 16473-18-0 1-(methoxy)-3-(fluoromethyl)benzene 
• 874-98-6 1-bromomethyl-3-methoxybenzene 
• 78358-11-9 methanesulfonic acid 3-methoxy-benzyl ester 
• 61456-44-8 1,1'-(m-methoxybenzylidene)dipiperidine 
• 591-31-1 3-methoxy-benzaldehyde 

Downstream Products

• 73279-04-6 3-[1-piperidinylmethyl]phenol 
• 1413927-76-0 C₁₃H₁₉NOSe 
• 1413927-74-8 C₂₆H₃₆N₂O₂Se₂ 
• 1413928-07-0 C₁₃H₁₉NO₂Se 

Relevant articles and documents

Palladium(ii)-catalysed ortho-arylation of N-benzylpiperidines

PdII-catalysed ortho-arylation of benzylic heterocycles with arylboronic acid pinacol esters (Ar-BPin) via directed C-H bond activation to generate the desired biaryl products is reported. This methodology is efficient and applicable to a wide range of functionalised Ar-BPin and benzylic heterocycles, allowing the direct synthesis of important biaryl motifs in modest to good yield. This journal is

Method for synthesizing Roxatidine intermediate 3-(1-piperidinyl methyl) phenol

The invention discloses a method for synthesizing Roxatidine intermediate 3-(1-piperidinyl methyl) phenol and relates to the technical field of organic synthesis. M-anisyl alcohol which is cheap and easy to obtain is used as a raw material and firstly reacts with sulfinyl chloride to produce m-methoxybenzyl chloride, then the m-methoxybenzyl chloride reacts with piperidine to produce 3-(1-piperidinyl methyl) anisole, and finally demethoxylation is performed in hydrobromic acid to obtain the target product 3-(1-piperidinyl methyl) phenol. The route is clear, the yield is high, the amount of produced waste water, gas and residues is small, the recycling of solvent can be realized, the preparation cost is reduced and the cost is less than half of the cost of the original route.

Base-promoted N-alkylation using formamides as the N-sources in neat water

An efficient catalyst-free, alternative method for the C-N bond formation reaction of alkyl electrophiles using formamides as the N-sources was achieved under mild conditions. The reaction possesses the advantages of a broad range of substrates scope and wide functional group tolerance. It should also be noted that this process was performed using the environmentally benign water as the sole solvent, and high yield can also be achieved in ten-gram scale.