1075727-00-2 Usage
Description
(1R,2R)-1-[(3,4-Dimethoxyphenyl)methyl]-2-[3-(tert-butoxy)-3-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium benzenesulfonate is a complex organic compound with a unique molecular structure. It is characterized by its isoquinolinium core, which is substituted with various functional groups, including dimethoxyphenyl, t-butoxy, and oxopropyl moieties. (1R,2R)-1-[(3,4-Dimethoxyphenyl)methyl]-2-[3-(tert-butoxy)-3-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium benzenesulfonate is known for its potential applications in the pharmaceutical industry due to its structural diversity and ability to interact with various biological targets.
Uses
Used in Pharmaceutical Industry:
(1R,2R)-1-[(3,4-Dimethoxyphenyl)methyl]-2-[3-(tert-butoxy)-3-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium benzenesulfonate is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique structure allows it to serve as a building block for the development of new medications with potential therapeutic applications.
Used in Drug Synthesis:
(1R,2R)-1-[(3,4-Dimethoxyphenyl)methyl]-2-[3-(tert-butoxy)-3-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium benzenesulfonate is utilized in the synthesis of drugs targeting specific diseases and conditions. Its structural features enable it to be modified and optimized to enhance its pharmacological properties, such as potency, selectivity, and bioavailability. This makes it a valuable tool in the development of novel therapeutic agents.
Used in Medicinal Chemistry Research:
(1R,2R)-1-[(3,4-Dimethoxyphenyl)methyl]-2-[3-(tert-butoxy)-3-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium benzenesulfonate is also used in medicinal chemistry research to study the structure-activity relationships of various drug candidates. By understanding how this compound interacts with biological targets, researchers can gain insights into the design of more effective and safer drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 1075727-00-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,5,7,2 and 7 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1075727-00:
(9*1)+(8*0)+(7*7)+(6*5)+(5*7)+(4*2)+(3*7)+(2*0)+(1*0)=152
152 % 10 = 2
So 1075727-00-2 is a valid CAS Registry Number.
1075727-00-2Relevant articles and documents
Preparation method of cisatracurium besilate intermediate R, R'-cis-ester
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Paragraph 0035; 0039-0043; 0044; 0048-0052, (2020/05/08)
The invention discloses a preparation method of cisatracurium besilate intermediate R, R'-cis-ester. The stereoconfiguration of the R, R'-cis-ester is consistent with that of a target product cisatracurium besilate, main process impurities and degradation products are basically consistent with research impurities of a target product cisatracurium besilate, a perfect quality control method is established and comprises the steps that diastereoisomers and S-isomers are controlled, the problems of chiral center formation and chiral conversion do not exist in the subsequent production process, splitting is not needed, the content of the isomers in the finished product is controlled from the source, and the chirality of the final product cisatracurium besilate is guaranteed; and when the base poison material methyl benzenesulfonate is moved forwards to the synthesis of R, R'-cis-ester, so that the residual risk in the target product is greatly reduced, and the clinical use is safer and morereliable.
PROCESS FOR PRODUCING CISATRACURIUM COMPOUNDS AND ASSOCIATED INTERMEDIATES
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Page/Page column 34-36, (2008/12/08)
The present invention provides processes for producing isoquinolinium compounds, and for converting them into cisatracurium salts, e.g., cisatracurium besylate
