1075727-06-8 Usage
Description
2-(2-carboxyethyl)-1-[(3,4-dimethoxyphenyl)methyl]-,1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinolinium benzenesulfonate is a complex organic compound with a unique chemical structure. It is characterized by its isoquinolinium core, which is substituted with various functional groups, including a carboxyethyl group, a dimethoxyphenylmethyl group, and benzenesulfonate moiety. 2-(2-carboxyethyl)-1-[(3,4-dimethoxyphenyl)methyl]-,1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinolinium benzenesulfonate is likely to have specific interactions with biological systems due to its structural features and charge distribution.
Uses
Used in Pharmaceutical Industry:
2-(2-carboxyethyl)-1-[(3,4-dimethoxyphenyl)methyl]-,1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinolinium benzenesulfonate is used as an impurity in the production of Cisatracurium (C496700), a neuromuscular blocking agent. Its presence in the drug is crucial for ensuring the safety and efficacy of the medication, particularly in liver transplant patients.
Used in Research and Development:
2-(2-carboxyethyl)-1-[(3,4-dimethoxyphenyl)methyl]-,1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinolinium benzenesulfonate may also be utilized in research and development settings to study its interactions with various biological targets and to explore its potential therapeutic applications. The unique structural features of the compound could make it a valuable tool in the development of new drugs and therapies.
Used in Quality Control and Analysis:
In the pharmaceutical industry, 2-(2-carboxyethyl)-1-[(3,4-dimethoxyphenyl)methyl]-,1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinolinium benzenesulfonate can be used as a reference compound for quality control and analytical purposes. Its inclusion in standard test procedures can help ensure the purity and potency of Cisatracurium and other related drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 1075727-06-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,5,7,2 and 7 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1075727-06:
(9*1)+(8*0)+(7*7)+(6*5)+(5*7)+(4*2)+(3*7)+(2*0)+(1*6)=158
158 % 10 = 8
So 1075727-06-8 is a valid CAS Registry Number.
1075727-06-8Relevant articles and documents
Preparation method and application of cisatracurium besilate
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, (2021/05/12)
The invention provides a preparation method and application of cisatracurium besylate, and the preparation method comprises the following steps: (1) dissolving R-tetrahydropapaverine-N-acetyl-L-leucine salt, adjusting the pH value with an alkaline solution, and then mixing with methyl 3-bromopropionate and alkali for reaction to obtain an intermediate A; (2) mixing and reacting the intermediate A obtained in the step (1) with alkali to obtain an intermediate B; (3) mixing and reacting the intermediate B obtained in the step (2) with a methylation reagent to obtain an intermediate C; and (4) mixing and reacting the intermediate C obtained in the step (3), a catalyst and a dehydrating agent to obtain cisatracurium besylate. The preparation method provided by the invention is safe in production process, high in yield, few in isomer and low in maximum single impurity.
PROCESS FOR PRODUCING CISATRACURIUM COMPOUNDS AND ASSOCIATED INTERMEDIATES
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Page/Page column 39, (2008/12/08)
The present invention provides processes for producing isoquinolinium compounds, and for converting them into cisatracurium salts, e.g., cisatracurium besylate