109745-70-2

Basic information

• Product Name: methyl glyoxylate methyl hemi-acetal
• CAS NO: 109745-70-2
• Molecular Weight: 120.105
• Mol File: 109745-70-2.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: methyl glyoxylate methyl hemi-acetal(CAS DataBase Reference)
• NIST Chemistry Reference: methyl glyoxylate methyl hemi-acetal(109745-70-2)
• EPA Substance Registry System: methyl glyoxylate methyl hemi-acetal(109745-70-2)

Safety Data

• Hazardous Substances Data: 109745-70-2(Hazardous Substances Data)

Upstream product

• 33414-80-1 2,4,6-trinitro anilino acetic acid ethyl ester 
• 124-41-4 sodium methylate 
• 107-31-3 Methyl formate 
• 98-01-1 furfural 
• 67-56-1 methanol 
• 10028-15-6 ozone 
• 292638-85-8 acrylic acid methyl ester 
• 922-68-9 Methyl glyoxylate 
• 563-96-2 2,2-dihydroxyacetic acid 
• 131543-46-9 Glyoxal 
• 298-12-4 Glyoxilic acid 

Downstream Products

• 89-91-8 Methyl dimethoxyacetate 
• 150749-03-4 methyl 2-(tert-butoxycarbonylamino)-2-hydroxyacetate 
• 71350-58-8 methoxycarbonyl aminal 
• 203914-82-3 [2-Phenyl-6,7-dihydro-5H-quinazolin-(8E)-ylidene]-acetic acid methyl ester 
• 77426-68-7 methyl 2-(benzyloxyamino)-3-methylbutanoate 
• 1196-57-2 2-hydroxyquinoxaline 
• 31767-13-2 methyl 2-(hydroxyimino)ethanoate 
• 875433-40-2 methyl 2-(1,3-dimethyl-2-oxocyclohexyl)-2-methoxyacetate 
• 173201-94-0 methyl N-(diphenylmethyl)iminoacetate 
• 461-72-3 2,4-imidazolidinedione 
• 1239579-39-5 (2Z,2'E)-dimethyl 2,2'-((1S,3S,7R,11S,15S,17R,21R,23S,25S,E)-25-acetoxy-17-((R)-1-((benzyloxy)methoxy)ethyl)-21-((tertbutyldiphenylsilyl)oxy)-11-methoxy-10,10,26,26-tetramethyl-12,19-dioxo-18,27,28,29-tetraoxatetracyclo[21.3.1.1(3,7).1(11,15)]nonacos-8-ene-5,13-diylidene)diacetate 
• 199807-77-7 (+/-)-methyl 2-azabicyclo[2.2.1]hept-5-ene-3-exo-carboxylate 
• 199807-77-7 (+/-)-2-azabicyclo[2.2.1]hept-5-ene-3-endo-carboxylate 
• 57451-13-5 (E)-[(phenylmethoxy)imino] acetic acid methyl ester 

Relevant articles and documents

SYNTHESE HETEROCYCLISCHER -OXO-ESSIGSAEUREESTER MIT EINEM NEUEN ACYLANIONAEQUIVALENT

The synthesis of new heterocyclic -oxo-acetic acid esters with the novel and easily available acylanion equivalent 5 is described.

Imidazole based solid-supported catalysts for the benzoin condensation

New polymer-supported imidazolium salts have been synthesised, and their utility as pre-catalysts in the benzoin reaction has been demonstrated.

POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF HIV INFECTIONS

Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, X, Y1, Y2, or L are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Experimental and DFT study of the aza-Diels-Alder reaction between cyclopentadiene and protonated benzylimine derivated from glyoxylates

The Diels-Alder reaction of protonated N-benzyl imine of methyl glyoxylate with cyclopentadiene in different solvents gave mixtures of exo/endo adducts. The exo/endo selectivity of the reaction was elucidated by NMR experiments. Theoretical calculations by means of density functional theory (DFT) at the B3LYP/6-31G(d) level have also been performed to elucidate the molecular mechanism of this reaction. The DFT results suggest a highly asynchronous concerted mechanism, which in turn can explain the preferred exo stereoselectivity of the reaction. Inclusion of solvent effects enhances the exo selectivity, and this effect increases with the polarity of the solvent, in good agreement with the experimental findings.