110451-87-1Relevant articles and documents
Total Synthesis of (±)-Pestalachloride C and (±)-Pestalachloride D through a Biomimetic Knoevenagel/Hetero-Diels-Alder Cascade
Arredondo, Vanessa,Roa, Daniel E.,Yan, Songyuan,Liu-Smith, Feng,Van Vranken, David L.
supporting information, p. 1755 - 1759 (2019/03/20)
A concise total synthesis of (±)-pestalachloride C and (±)-pestalachloride D was achieved through a Knoevenagel/hetero-Diels-Alder cascade reaction to test the nonenzymatic biosynthetic hypothesis of Shao, Wang, and co-workers. The cascade reaction generates a mixture of racemic indano[2,1-c]chromans like those found in the natural products.
Phosphine/palladium-catalyzed syntheses of alkylidene phthalans, 3-deoxyisoochracinic acid, isoochracinic acid, and isoochracinol
Fan, Yi Chiao,Kwon, Ohyun
, p. 3264 - 3267 (2012/08/28)
In this study we used sequential catalysis-PPh3-catalyzed nucleophilic addition followed by Pd(0)-catalyzed Heck cyclization-to construct complex functionalized alkylidene phthalans rapidly, in high yields, and with good stereoselectivities (E/Z ratios of up to 1:22). The scope of this Michael-Heck reaction includes substrates bearing various substituents around the alkylidene phthalan backbone. Applying this efficient sequential catalysis, we accomplished concise total syntheses of 3-deoxyisoochacinic acid, isoochracinic acid, and isoochracinol.
Simple and regioselective oxyiodination of aromatic compounds with ammonium iodide and Oxone
Krishna Mohan,Narender,Kulkarni
, p. 8015 - 8018 (2007/10/03)
Oxyiodination of aromatic compounds using NH4I and Oxone gives high yields and selectivity. A simple method for the iodination of aromatic compounds using NH4I as the iodine source and Oxone as the oxidant is described.
