58432-83-0

Basic information

• Product Name: Benzene, 1-(chloromethyl)-2-iodo-4,5-dimethoxy-
• CAS NO: 58432-83-0
• Molecular Formula: C9H10ClIO2
• Molecular Weight: 312.535
• Mol File: 58432-83-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(chloromethyl)-2-iodo-4,5-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(chloromethyl)-2-iodo-4,5-dimethoxy-(58432-83-0)
• EPA Substance Registry System: Benzene, 1-(chloromethyl)-2-iodo-4,5-dimethoxy-(58432-83-0)

Safety Data

• Hazardous Substances Data: 58432-83-0(Hazardous Substances Data)

Upstream product

• 110451-87-1 2-bromomethyl-1-iodo-4,5-dimethoxybenzene 
• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 
• 61203-53-0 2-iodo-4,5-dimethoxybenzaldehyde 
• 103477-58-3 2-(2-bromo-4,5-dimethoxyphenyl)-1,3-dioxolane 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Downstream Products

• 128428-15-9 3-(2-Iodo-3,4-dimethoxy-benzyloxy)-7-methoxy-chromen-4-one 
• 141341-66-4 3-(2'-iodo-4',5'-dimethoxybenzyloxy)-7-methoxychromen-4-one 
• 58432-84-1 2-(2-iodo-4,5-dimethoxyphenyl)acetonitrile 
• 63856-82-6 1-(3,4-Dimethoxy-phenyl)-2-(2-iodo-4,5-dimethoxy-phenyl)-ethanone 
• 299215-71-7 (E)-1,2-bis(4,5-dimethoxy-2-iodophenyl)-N,N-dimethylethenylamine 
• 110451-87-1 2-bromomethyl-1-iodo-4,5-dimethoxybenzene 
• 796087-49-5 1-(2'-iodo-4',5'-dimethoxybenzyl)-indole-2,3-dione 
• 319427-28-6 1-(2'-iodo-4',5'-dimethoxybenzyl)-3,3-ethylenedioxyindol-2-one 
• 61203-53-0 2-iodo-4,5-dimethoxybenzaldehyde 
• 293732-19-1 (4,5-dimethoxy-2-iodophenyl)methyl bromide 
• 299216-03-8 5-(4,5-dimethoxy-2-iodophenyl)-4-(2-iodophenyl)isoxazole 
• 299216-05-0 4-(4,5-dimethoxy-2-iodophenyl)-5-(2-iodophenyl)isoxazole 
• 299216-01-6 4,5-bis(4,5-dimethoxy-2-iodophenyl)isoxazole 
• 299215-42-2 2-(N,N-dimethylamino)-2-(4,5-dimethoxy-2-iodophenyl)acetonitrile 

Relevant articles and documents

The asymmetric synthesis of aryltetralin lignans: (-)-isolariciresinol dimethyl ether and (-)-deoxysikkimotoxin

The total asymmetric syntheses of (-)-isolariciresinol dimethyl ether (6) and (-)-deoxysikkimotoxin (7) have been carried out, in an attempt to exploit a synthetic strategy recently developed for the synthesis of (-)-deoxypodophyllotoxin (1, R1 = -CH2-, Ar = 3,4,5-trimethoxyphenyl). In so doing, a generalized method for the synthesis of aryltetralin lignans has been developed that should be applicable to a variety of substitution patterns and stereochemistries. A one-pot, 100% regio-selective reduction-lactonization procedure has been developed for the conversion of the ester 18b to (-)-deoxysikkimotoxin, which gave 93% isolated yield in that step.