113311-21-0

Basic information

• Product Name: L-Glutamic acid, N-[4-(methylamino)benzoyl]-, bis(1,1-dimethylethyl) ester
• CAS NO: 113311-21-0
• Molecular Formula: C21H32N2O5
• Molecular Weight: 392.495
• Mol File: 113311-21-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: L-Glutamic acid, N-[4-(methylamino)benzoyl]-, bis(1,1-dimethylethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Glutamic acid, N-[4-(methylamino)benzoyl]-, bis(1,1-dimethylethyl) ester(113311-21-0)
• EPA Substance Registry System: L-Glutamic acid, N-[4-(methylamino)benzoyl]-, bis(1,1-dimethylethyl) ester(113311-21-0)

Safety Data

• Hazardous Substances Data: 113311-21-0(Hazardous Substances Data)

Upstream product

• 56-86-0 L-glutamic acid 
• 16874-06-9 di-tert-butyl L-glutamate 
• 66891-86-9 benzyl (4-(chlorocarbonyl)phenyl)(methyl)carbamate 
• 2528-30-5 4-<<(benzyloxy)carbonyl>methylamino>benzoic acid 
• 875667-98-4 di-tert-butyl N-[4-(N-benzyloxycarbonyl-N-methyl)aminobenzoyl]-L-glutamate 
• 10541-83-0 N-methyl-p-aminobenzoic acid 

Downstream Products

• 113311-20-9 methotrexate-2,4a,6-⁽¹³⁾C₃ di-t-butyl ester 
• 86669-33-2 methotrexate di-t-butyl ester 
• 113311-25-4 2,4-diamino-6-dibromomethylpteridine 

Relevant articles and documents

PRODRUGS ACTIVATED BY REACTIVE OXYGEN SPECIES FOR USE IN THE TREATMENT OF INFLAMMATORY DISEASES AND CANCER

Prodrugs activated predominantly or exclusively in inflammatory tissue, more particularly prodrugs of methotrexate and derivatives thereof, which are selectively activated by Reactive Oxygen Species (ROS) in inflammatory tissues associated with cancer and inflammatory diseases, as well as method for preparing said prodrugs.