1152980-49-8 Usage
Pyrazole derivative
It is a derivative of the pyrazole ring a five-membered heterocyclic compound consisting of four carbon atoms and one nitrogen atom in the ring.
tert-Butyl group attachment
The compound has a tert-butyl group (C4H9) attached to the nitrogen atom, which influences its chemical properties and reactivity.
Use in organic synthesis
1-tert-Butyl-1H-pyrazol-3-amine serves as a building block for the preparation of various pharmaceuticals and agrochemicals, making it a valuable intermediate in the synthesis of different compounds.
Ligand in coordination chemistry
This chemical can act as a ligand, binding to metal ions to form coordination complexes, which can be used in various applications, such as catalysis and material science.
Reagent in organic reactions
1-tert-Butyl-1H-pyrazol-3-amine can be used as a reagent in organic reactions, facilitating specific chemical transformations and helping to synthesize target compounds.
Potential applications in medicinal chemistry and drug development
Due to its chemical structure and properties, 1-tert-Butyl-1H-pyrazol-3-amine may have potential applications in the field of medicinal chemistry, contributing to the development of new drugs and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 1152980-49-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,2,9,8 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1152980-49:
(9*1)+(8*1)+(7*5)+(6*2)+(5*9)+(4*8)+(3*0)+(2*4)+(1*9)=158
158 % 10 = 8
So 1152980-49-8 is a valid CAS Registry Number.
1152980-49-8Relevant articles and documents
Gas-phase synthesis of pyrazolo[3,4- b ]pyridin-4-ones
Mackay, Martha,Nortcliffe, Andrew,McNab, Hamish,Hulme, Alison N.
, p. 242 - 248 (2015)
Flash vacuum pyrolysis (FVP) at 500-600 °C of 1-substituted pyrazolylaminomethylene derivatives of Meldrum's acid provides 1-substituted pyrazolo[3,4-b]pyridin-4-ones in high yields. If the 1-substituent is a tert-butyl group, FVP at 750-850 °C causes elimination of 2-methyl-1-propene to give the parent pyrazolo[3,4-b]pyridin-4-one.
SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME
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Page/Page column 134, (2016/09/15)
ABSTRACT The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.
IMIDAZOPYRIDAZINE COMPOUNDS
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Page/Page column 59-60, (2013/05/22)
The present invention relates to the use of novel compounds of formula (I): wherein all variable substituents are defined as described herein, which are SYK inhibitors and are useful for the treatment of auto-immune and inflammatory diseases.
