1174456-59-7

Basic information

• Product Name: 5-bromo-4-chloroindoxyl α-D-galactopyranoside
• CAS NO: 1174456-59-7
• Molecular Weight: 408.633
• Mol File: 1174456-59-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 5-bromo-4-chloroindoxyl α-D-galactopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-4-chloroindoxyl α-D-galactopyranoside(1174456-59-7)
• EPA Substance Registry System: 5-bromo-4-chloroindoxyl α-D-galactopyranoside(1174456-59-7)

Safety Data

• Hazardous Substances Data: 1174456-59-7(Hazardous Substances Data)

Upstream product

• 3030-06-6 1-acetyl-5-bromo-4-chloro-3-indolyl acetate 
• 125328-76-9 1-acetyl-5-bromo-4-chloro-3-hydroxyindole 
• 116270-39-4 1-acetyl-5-bromo-4-chloroindolin-3-one 
• 3068-32-4 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside 
• 125328-80-5 N-(4-bromo-3-chloro-2-methylphenyl)acetamide 
• 627531-47-9 4-amino-2-chloro-3-methylbromobenzene 
• 125328-75-8 (N-acetyl-5-bromo-4-chloro-indol-3-yl) 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside 
• 1607828-55-6 C₂₆H₂₇BrClNO₁₂ 
• 1447125-25-8 C₁₅H₁₅BrClNO₄ 
• 1447125-22-5 C₁₃H₉BrClNO₅ 
• 943138-45-2 5-bromo-6-chloro-isatoic anhydride 
• 1447125-28-1 5-bromo-4-chloroindoxylic acid allyl ester 
• 3030-19-1 2-amino-5-bromo-6-chlorobenzoic acid 
• 125328-77-0 N-acetyl-5-bromo-6-chloroanthranilic acid 

Relevant articles and documents

Synthesis of precipitating chromogenic/fluorogenic β-glucosidase/β-galactosidase substrates by a new method and their application in the visual detection of foodborne pathogenic bacteria

We developed a new efficient method for the synthesis of important indoxyl glycoside substrates for β-glucosidase and β-galactosidase by using 1-acetylindol-3-ones as intermediates. This method was used to synthesise novel precipitating fluorogenic substrates for β-glucosidase based on 2-(benzothiazol-2′-yl)-phenols. We also assessed the application of these substrates in the detection of foodborne pathogenic bacteria.

Synthesis method of glucoside based on indoxyl derivative and 2-(benzothiazol-2'-yl)phenol derivative

The invention discloses a synthesis method of glucoside based on an indoxyl derivative and a 2-(benzothiazol-2'-yl)phenol derivative. The general formula of a synthetic equation of the synthesis method is as shown in the description; the Ar-OH represents aromatic phenol or a ketonic compound thereof, and is used as a glycosyl receptor in a glycosylation reaction; the G-X represents halogenated sugar, and is used as a glycosyl donor in the glycosylation reaction. According to the synthesis method of the glucoside based on the indoxyl derivative and the 2-(benzothiazol-2'-yl)phenol derivative, a 1-acetylindolin-3-one derivative is selected and used as an intermediate; a novel synthesis method is researched and developed to prepare the glucoside based on the indoxyl derivative; a novel glycosidase fluorescence probe based on a BTP ((2-benzothiazol-2'-yl)phenyl) derivative is synthesized by applying the method; meanwhile, the application effects of the glucoside based on the indoxyl derivative and the glycosidase fluorescence probe are investigated. The glucoside based on the indoxyl derivative and the 2-(benzothiazol-2'-yl)phenol derivative can be used as glycosidase substrates, and is used for the positioning analytic detection and screening on the corresponding glycosidase, a microorganism using the corresponding glycosidase as a characteristic target, and the like.

Enzymatic synthesis of colorimetric substrates to determine α-2,3- and α-2,6-specific neuraminidase activity

Glycoconjugates containing either terminal α-2,3- or α-2,6-Neu5Ac-Gal disaccharides are found on cell surfaces of many animal glycans. Each linkage can be specifically recognized by lectins and enzymes such as neuraminidases. Here we describe a one-step enzymatic synthesis of two colorimetric substrates that allow for fast distinction of specific neuraminidase activity. The Royal Society of Chemistry 2013.