121612-73-5

Basic information

• Product Name: (S)-(-)-N-(thieno<2,3-b>pyridine-5-carbonyl)phenylalaninol
• Synonyms: (S)-(-)-N-(thieno<2,3-b>pyridine-5-carbonyl)phenylalaninol
• CAS NO: 121612-73-5
• Molecular Weight: 312.392
• Mol File: 121612-73-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-(-)-N-(thieno<2,3-b>pyridine-5-carbonyl)phenylalaninol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(-)-N-(thieno<2,3-b>pyridine-5-carbonyl)phenylalaninol(121612-73-5)
• EPA Substance Registry System: (S)-(-)-N-(thieno<2,3-b>pyridine-5-carbonyl)phenylalaninol(121612-73-5)

Safety Data

• Hazardous Substances Data: 121612-73-5(Hazardous Substances Data)

Upstream product

• 63-91-2 L-phenylalanine 
• 117390-38-2 thieno<2,3-b>pyridine-5-carboxylic acid 
• 3182-95-4 L-Phenylalaninol 
• 121612-70-2 Thieno[2,3-b]pyridine-5-carbonyl chloride 

Downstream Products

• 121612-84-8 (S)-N-(N-methyl-4,7-dihydrothieno<2,3-b>pyridine-5-carbonyl)phenylalaninol 
• 121612-79-1 5-((S)-1-Hydroxymethyl-2-phenyl-ethylcarbamoyl)-7-methyl-thieno[2,3-b]pyridin-7-ium; iodide 
• 4358-87-6 (RS)-methyl mandelate 

Relevant articles and documents

Improvement in the Enantioselectivity of the Hydrogen Transfer with NADH Models Bearing Amino Alcohols as Chiral Auxiliaries

Chiral amino alcohols have been linked to the γ-carbonyl group of the 5,7-dihydrothienopyridines (4a-d).These models are much more easily handled in mild conditions than common NADH models.The factors affecting enantiomeric excess have been studied, e.g. influence of temperature, polarity of solvents, magnesium concentration, and hydrogen bonding.By appropriate modifications of the chiral auxiliary, the rigidity of the ternary complex: model-Mg2+-substrate involved has been enhanced.In this way a high enantiomeric excess has been obtained.