124306-44-1

Basic information

• Product Name: (E)-2-methyl-1-phenyl-2-penten-1-one
• Synonyms: (E)-2-methyl-1-phenyl-2-penten-1-one
• CAS NO: 124306-44-1
• Molecular Weight: 174.243
• Mol File: 124306-44-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (E)-2-methyl-1-phenyl-2-penten-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-methyl-1-phenyl-2-penten-1-one(124306-44-1)
• EPA Substance Registry System: (E)-2-methyl-1-phenyl-2-penten-1-one(124306-44-1)

Safety Data

• Hazardous Substances Data: 124306-44-1(Hazardous Substances Data)

Upstream product

• 93-55-0 1-phenyl-propan-1-one 
• 58625-96-0 ethyl 2-methyl-2-pentenoate 
• 17180-49-3 2-methyl-1-phenylpent-4-en-1-one 
• 627-21-4 2-Pentyne 
• 100-52-7 benzaldehyde 
• 37471-46-8 1-phenyl-1-trimethylsiloxypropene 
• 71268-59-2 (E)-1-phenyl-1-(trimethylsiloxy)propene 
• 79314-55-9 3-hydroxy-2-methyl-1-phenylpentan-1-one 
• 16837-43-7 2-benzoylpropanal 
• 925-90-6 ethylmagnesium bromide 

Downstream Products

• 857973-57-0 2-methyl-1,3-diphenyl-pentan-1-one 
• 90013-12-0 (R)-2-methyl-1-phenyl-1-pentanone 
• 872884-41-8 (S)-(+)-2-methyl-1-phenylpentan-1-one 
• 1312031-65-4 C₂₀H₂₁ClO₂S 
• 87514-18-9 Trimethyl-((1Z,3E)-2-methyl-1-phenyl-penta-1,3-dienyloxy)-silane 

Relevant articles and documents

Borane-Catalyzed Direct Asymmetric Vinylogous Mannich Reactions of Acyclic α,β-Unsaturated Ketones

Herein, we report that, by using chiral bicyclic bisborane catalysts, we have achieved the first highly regio-, diastereo-, and enantioselective direct asymmetric vinylogous Mannich reactions of acyclic α,β-unsaturated ketones. The strong Lewis acidity and steric bulk of the bisborane catalysts were essential for the observed high yields and selectivities.

Pd-Boron-Catalyzed One Carbon Isomerization of Olefins: Water Assisted Process at Room Temperature

A palladium-boronate/borane-system -catalyzed isomerization of olefins has been uncovered. An efficient catalytic combination of [Pd(OAc)2]3-boronate-PCy3-enabled olefin isomerization at 80 °C has been investigated. Addition of water to the reaction showed a remarkable improvement and the isomerization occurred at ambient temperature. These catalytic systems function efficiently for the isomerization of functionalized as well as unfunctionalized olefins. The catalytic conditions demonstrate the involvement of both nonhydride and metal-hydride medium and can be switchable with water as an additive.

Highly enantioselective synthesis of optically active ketones by iridium-catalyzed asymmetric hydrogenation

(Chemical Equation Presented) Close to perfect enantioselectivity (up to 99% ee, see scheme) is found for the formation of α-substituted ketones by the asymmetric hydrogenation of enones with an iridium-phosphinooxazoline catalyst. In an operationally simple process, both linear and cyclic substrates react well and afford the desired products in high yields. A wide variety of substituents are tolerated, thus making the method synthetically appealing.