1252801-60-7

Basic information

• Product Name: 1-(2-hydroxy-5-methoxy-4-(tetrahydro-2H-pyran-2-yloxy)phenyl)ethanone
• Synonyms: 1-(2-hydroxy-5-methoxy-4-(tetrahydro-2H-pyran-2-yloxy)phenyl)ethanone
• CAS NO: 1252801-60-7
• Molecular Weight: 266.294
• Mol File: 1252801-60-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(2-hydroxy-5-methoxy-4-(tetrahydro-2H-pyran-2-yloxy)phenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-hydroxy-5-methoxy-4-(tetrahydro-2H-pyran-2-yloxy)phenyl)ethanone(1252801-60-7)
• EPA Substance Registry System: 1-(2-hydroxy-5-methoxy-4-(tetrahydro-2H-pyran-2-yloxy)phenyl)ethanone(1252801-60-7)

Safety Data

• Hazardous Substances Data: 1252801-60-7(Hazardous Substances Data)

Upstream product

• 99179-72-3 3-acetoxy-4-methoxyphenol 
• 3749-36-8 2-hydroxymethyl-3,4-dihydro-2H-pyran 
• 7298-21-7 1-(2,4-dihydroxy-5-methoxyphenyl)ethan-1-one 
• 110-87-2 3,4-dihydro-2H-pyran 
• 117705-66-5 5-(hydroxymethyl)-2,4-dihydroxyacetophenone 

Downstream Products

• 1252801-69-6 C₁₇H₂₃NO₅ 
• 1252801-65-2 O⁷-benzyl glaziovianin A 
• 1415914-34-9 (E)-3-(dimethylamino)-1-(2-hydroxy-5-methoxy-4-(tetrahydro-2H-pyran-2-yloxy)phenyl)prop-2-en-1-one 

Relevant articles and documents

Practical synthesis of glaziovianin A, a cytotoxic isoflavone, and its O7-propargyl analogue

Glaziovianin A and its O7-propargyl analogue are potent cytotoxic isoflavones. We found that the O7-propargyl analogue completely arrested cell-cycle progression. We have achieved the large-scale synthesis of glaziovianin A and its O7-propargyl analogue for further in vivo experimentation.

Structure-activity relationship study of glaziovianin A against cell cycle progression and spindle formation of HeLa S3 cells

Various derivatives of glaziovianin A, an antitumor isoflavone, were synthesized, and the cytotoxicity of each against HeLa S3 cells was investigated. Compared to glaziovianin A, the O7-allyl derivative was found to be more cytotoxic