1415914-34-9Relevant articles and documents
Practical synthesis of glaziovianin A, a cytotoxic isoflavone, and its O7-propargyl analogue
Hayakawa, Ichiro,Shioda, Shuya,Ikedo, Akiyuki,Kigoshi, Hideo
, p. 544 - 549 (2014/05/06)
Glaziovianin A and its O7-propargyl analogue are potent cytotoxic isoflavones. We found that the O7-propargyl analogue completely arrested cell-cycle progression. We have achieved the large-scale synthesis of glaziovianin A and its O7-propargyl analogue for further in vivo experimentation.