1255919-01-7 Usage
Description
2-[2-ethoxy-5-(4-ethylpiperazine-1-sulfonyl)phenyl]-5-methyl-7-phenyl-3H-imidazo[5,1-f] [1,2,4]triazin-4-one is a complex organic compound with a unique chemical structure. It is characterized by the presence of an imidazo[5,1-f][1,2,4]triazin-4-one core, which is substituted with various functional groups, including an ethoxy group, an ethylpiperazine-1-sulfonyl group, and a methyl and phenyl group. 2-[2-ethoxy-5-(4-ethylpiperazine-1-sulfonyl)phenyl]-5-methyl-7-phenyl-3H-imidazo[5,1-f] [1,2,4]triazin-4-one exhibits a range of biological activities and has potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
2-[2-ethoxy-5-(4-ethylpiperazine-1-sulfonyl)phenyl]-5-methyl-7-phenyl-3H-imidazo[5,1-f] [1,2,4]triazin-4-one is used as a pharmaceutical compound for the treatment of erectile dysfunction. It functions as a selective phosphodiesterase type 5 (PDE5) inhibitor, which helps to increase blood flow to the penis and improve erectile function in men with erectile dysfunction.
Used in Research and Development:
2-[2-ethoxy-5-(4-ethylpiperazine-1-sulfonyl)phenyl]-5-methyl-7-phenyl-3H-imidazo[5,1-f] [1,2,4]triazin-4-one is also used in research and development for the discovery of new drugs and therapeutic agents. Its unique chemical structure and biological activities make it a valuable tool for studying various biological processes and identifying potential targets for drug development.
Used in Impurity Testing:
As an impurity of Vardenafil (V098001), 2-[2-ethoxy-5-(4-ethylpiperazine-1-sulfonyl)phenyl]-5-methyl-7-phenyl-3H-imidazo[5,1-f] [1,2,4]triazin-4-one is used in impurity testing to ensure the purity and quality of pharmaceutical products. This helps to maintain the safety and efficacy of medications and protect patients from potential adverse effects caused by impurities.
Check Digit Verification of cas no
The CAS Registry Mumber 1255919-01-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,5,9,1 and 9 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1255919-01:
(9*1)+(8*2)+(7*5)+(6*5)+(5*9)+(4*1)+(3*9)+(2*0)+(1*1)=167
167 % 10 = 7
So 1255919-01-7 is a valid CAS Registry Number.
1255919-01-7Relevant articles and documents
Synthesis and spectral characterization of related substances of vardenafil, an erectile dysfunction drug
Reddy, Vajrala Venkata,Naga Brahmeswara Rao, Mandava Venkata,Reddy, Ghanta Mahesh,Mukkanti, Khagga,Reddy, Ganta Madhusudhan
, p. 3513 - 3523 (2012/10/18)
Vardenafil hydrochloride trihydrate (Levitra) is used to treat erectile dysfunction (ED) and is an inhibitor of phosphodiesterase type 5 (PDE-5) enzyme. It maintains higher levels of cyclic guanosine monophosphate (cGMP), relaxes smooth muscles, promotes penile blood flow, and enhances erectile function. During the bulk drug synthesis of vardenafil hydrochloride trihydrate, six related substances (impurities), vardenafil dimer, vardenafil N-oxide, vardenafil glycene, vardenafil oxopiperazine, vardenafil oxoacetic acid, and phenyl vardenafil were identified, and these are reported herein for the first time. The present work describes the synthesis and characterization of these impurities.
