130753-15-0

Basic information

• Product Name: benzyl (1S,5R)-(-)-3-trimethylsiloxy-8-azabicyclo<3.2.1>oct-2-ene-8-carboxylate
• Synonyms: benzyl (1S,5R)-(-)-3-trimethylsiloxy-8-azabicyclo<3.2.1>oct-2-ene-8-carboxylate
• CAS NO: 130753-15-0
• Molecular Weight: 331.487
• Mol File: 130753-15-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: benzyl (1S,5R)-(-)-3-trimethylsiloxy-8-azabicyclo<3.2.1>oct-2-ene-8-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (1S,5R)-(-)-3-trimethylsiloxy-8-azabicyclo<3.2.1>oct-2-ene-8-carboxylate(130753-15-0)
• EPA Substance Registry System: benzyl (1S,5R)-(-)-3-trimethylsiloxy-8-azabicyclo<3.2.1>oct-2-ene-8-carboxylate(130753-15-0)

Safety Data

• Hazardous Substances Data: 130753-15-0(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 28957-72-4 N-benzylnortropinone 
• 542-05-2 acetonedicarboxylic acid 
• 130753-13-8 benzyl 3-oxo-8-azabicyclo[3,2,1]octane-8-carboxylate 

Downstream Products

• 130753-18-3 benzyl (2S,5R)-(-)-2-(methoxymethoxymethyl)-5-(2-p-tolylsulfonyloxyethyl)pyrrolidine-1-carboxylate 
• 192053-57-9 (2R,5S)-2-Methoxycarbonylmethyl-5-methoxymethoxymethyl-pyrrolidine-1-carboxylic acid benzyl ester 
• 130753-22-9 benzyl (2S,5S)-2-(but-1-enyl)-5-(4-oxopentyl)pyrrolidine-1-carboxylate 
• 130753-20-7 benzyl (2S,5S)-(-)-2-(methoxymethoxymethyl)-5-pent-4-enylpyrrolidine-1-carboxylate 
• 130753-19-4 benzyl (2R,5S)-(+)-2-(2-iodoethyl)-5-(methoxymethoxymethyl)pyrrolidine-1-carboxylate 
• 130753-17-2 benzyl (2R,5S)-(-)-2-(2-hydroxyethyl)-5-(methoxymethoxymethyl)pyrrolidine-1-carboxylate 
• 130753-23-0 benzyl (2R,5S)-2-ethenyl-5-(methoxymethoxymethyl)pyrrolidine-1-carboxylate 
• 130753-14-9 benzyl (2R,5S)-(-)-2-(hydroxymethyl)-5-(methoxymethoxymethyl)pyrrolidine-1-carboxylate 
• 130753-21-8 benzyl (2S,5S)-2-but-1-enyl-5-pent-4-enylpyrrolidine-1-carboxylate 
• 130753-16-1 methyl (2R,5S)-(-)-1-benzyloxycarbonyl-5-hydroxymethylpyrrolidin-2-ylethanoate 

Relevant articles and documents

Bicyclo[3.3.1]nonanes as synthetic intermediates. Part 19. Asymmetric cleavage of ω-azabicyclo[3.n.1]alkan-3-ones at the 'fork head'

Asymmetric cleavage of ω-azabicyclo[3.n.1]alkan-3-ones was achieved by asymmetric deprotonation at the 'fork head' ketone system with Koga's chiral base and subsequent ozonolysis of the resulting chiral silyl enol ether to give the cis-α,α′-disubstituted piperidine, pyrrolidine and hexahydroazepine, respectively, in high enantiomeric excess.