130753-19-4

Basic information

• Product Name: benzyl (2R,5S)-(+)-2-(2-iodoethyl)-5-(methoxymethoxymethyl)pyrrolidine-1-carboxylate
• Synonyms: benzyl (2R,5S)-(+)-2-(2-iodoethyl)-5-(methoxymethoxymethyl)pyrrolidine-1-carboxylate
• CAS NO: 130753-19-4
• Molecular Weight: 433.286
• Mol File: 130753-19-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: benzyl (2R,5S)-(+)-2-(2-iodoethyl)-5-(methoxymethoxymethyl)pyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (2R,5S)-(+)-2-(2-iodoethyl)-5-(methoxymethoxymethyl)pyrrolidine-1-carboxylate(130753-19-4)
• EPA Substance Registry System: benzyl (2R,5S)-(+)-2-(2-iodoethyl)-5-(methoxymethoxymethyl)pyrrolidine-1-carboxylate(130753-19-4)

Safety Data

• Hazardous Substances Data: 130753-19-4(Hazardous Substances Data)

Upstream product

• 192053-57-9 (2R,5S)-2-Methoxycarbonylmethyl-5-methoxymethoxymethyl-pyrrolidine-1-carboxylic acid benzyl ester 
• 130753-15-0 benzyl (1S,5R)-(-)-3-trimethylsiloxy-8-azabicyclo<3.2.1>oct-2-ene-8-carboxylate 
• 130753-16-1 methyl (2R,5S)-(-)-1-benzyloxycarbonyl-5-hydroxymethylpyrrolidin-2-ylethanoate 
• 130753-13-8 benzyl 3-oxo-8-azabicyclo[3,2,1]octane-8-carboxylate 
• 130753-17-2 benzyl (2R,5S)-(-)-2-(2-hydroxyethyl)-5-(methoxymethoxymethyl)pyrrolidine-1-carboxylate 
• 130753-18-3 benzyl (2S,5R)-(-)-2-(methoxymethoxymethyl)-5-(2-p-tolylsulfonyloxyethyl)pyrrolidine-1-carboxylate 

Downstream Products

• 130753-21-8 benzyl (2S,5S)-2-but-1-enyl-5-pent-4-enylpyrrolidine-1-carboxylate 
• 130753-22-9 benzyl (2S,5S)-2-(but-1-enyl)-5-(4-oxopentyl)pyrrolidine-1-carboxylate 
• 130753-20-7 benzyl (2S,5S)-(-)-2-(methoxymethoxymethyl)-5-pent-4-enylpyrrolidine-1-carboxylate 

Relevant articles and documents

Bicyclo[3.3.1]nonanes as synthetic intermediates. Part 20. Asymmetric synthesis of the indolizidine alkaloids monomorine I and indolizidine 223AB

Total syntheses of the indolizidine alkaloids monomorine I and indolizidine 223AB have been achieved by starting from the chiral cis-2,5-disubstituted pyrrolidine or cis-2,6-disubstituted piperidine obtained from the asymmetric cleavage of 8-azabicyclo[3.2.1]octan-3-one or 9-azabicyclo[3.3.1]nonan-3-one at the 'fork head'.