1308663-62-8

Basic information

• Product Name: (1R,2S)-2-(benzhydrylamino)-3-fluoro-1-(4-(methylsulfonyl)phenyl)propan-1-ol
• Synonyms: (1R,2S)-2-(benzhydrylamino)-3-fluoro-1-(4-(methylsulfonyl)phenyl)propan-1-ol
• CAS NO: 1308663-62-8
• Molecular Weight: 413.513
• Mol File: 1308663-62-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2S)-2-(benzhydrylamino)-3-fluoro-1-(4-(methylsulfonyl)phenyl)propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-2-(benzhydrylamino)-3-fluoro-1-(4-(methylsulfonyl)phenyl)propan-1-ol(1308663-62-8)
• EPA Substance Registry System: (1R,2S)-2-(benzhydrylamino)-3-fluoro-1-(4-(methylsulfonyl)phenyl)propan-1-ol(1308663-62-8)

Safety Data

• Hazardous Substances Data: 1308663-62-8(Hazardous Substances Data)

Upstream product

• 91-00-9 Benzhydrylamine 
• 5398-77-6 para-methanesulfonylbenzaldehyde 
• 1284258-88-3 N-(4-(methylsulfonyl)benzylidene)diphenylmethanamine 
• 1308663-57-1 (2S,3S)-1-benzhydryl-2-(fluoromethyl)-3-(4-(methylsulfonyl)phenyl)aziridine 
• 1284258-90-7 ((2S,3S)-1-benzhydryl-3-(4-(methylsulfonyl)phenyl)aziridin-2-yl)methanol 
• 1284258-89-4 (2S,3S)-ethyl 1-benzhydryl-3-(4-(methylsulfonyl)phenyl)aziridine-2-carboxylate 

Downstream Products

• 76639-93-5 (1R,2S)-2-amino-3-fluoro-1-<4-(methylsulphonyl)phenyl>-1-propanol 
• 73231-34-2 Florfenicol 

Relevant articles and documents

An efficient enantioselective synthesis of florfenicol via asymmetric aziridination

An efficient enantioselective synthesis of florfenicol is accomplished in 44.7% overall yield from commercially available p-(methylsulfonyl)benzaldehyde. Key features of this synthesis are the asymmetric aziridination reaction mediated by the Wulff's catalyst in situ derived from (R)-VANOL and diastereoselectively ring-opening of (2S,3S)-fluoroaziridine 13.